Skip to main content Accessibility help
×
Home

MCP-1 and MIP-2 levels during Echinococcus granulosus infections in mice

  • Y. Theodorides (a1), S. Frydas (a1), T. Rallis (a2), K. Adamama-Moraitou (a2), R. Papazahariadou (a1), C. Batzios (a3) and P. Conti (a4)...

Abstract

Ten BALB/c mice were infected with the cestode Echinococcus granulosus. After the infection, serum was collected at different periods of time and monocyte chemotactic protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) were determined. The level of MCP-1 increased from 290±12 pg ml-1 (mean±SD) at day 20 post infection (p.i.), to a maximum of 820±23 pg ml-1 on day 60 p.i., then decreased to 460±12.6 pg ml-1 on day 130 p.i. A second peak was observed at day 150 p.i. In addition, MIP-2 was detectable in serum as late as day 100 p.i. The highest level (100±11 pg ml-1) was observed on day 130 p.i., and decreased thereafter. Serum from noninfected animals (controls) contained no detectable levels of either MCP-1 or MIP-2. However, MCP-1 and MIP-2 appear to be implicated in E. granulosus infections, but their exact role during the disease is under determination.

Copyright

Corresponding author

*Author for correspondence Fax: +30 31 999947 E-mail: trallis@vet.auth.gr

MCP-1 and MIP-2 levels during Echinococcus granulosus infections in mice

  • Y. Theodorides (a1), S. Frydas (a1), T. Rallis (a2), K. Adamama-Moraitou (a2), R. Papazahariadou (a1), C. Batzios (a3) and P. Conti (a4)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed