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Health informatics model for helminthiasis in Thailand

  • C. Nithikathkul (a1), A. Trevanich (a2), T. Wongsaroj (a3), C. Wongsawad (a4) and P. Reungsang (a5)...

Abstract

At the beginning of the new millennium, helminth infections continue to be prevalent, particularly among impoverished populations. This study attempts to create the first health informatics model of helminthiasis in Thailand. The authors investigate how a health informatics model could be used to predict the control and eradication in a national control campaign. Fish-borne helminthiasis caused by Opisthorchis viverrini remains a major public health problem in many parts of South-East Asia, including Thailand, Lao PDR, Vietnam and Cambodia. The epicentre of this disease is located in north-east Thailand, where high prevalence coexists with a high incidence of cholangiocarcinoma (CHCA). The current report was conducted to determine a mathematical model of surveillance for helminthiasis while also using a geographic information system. The fish-borne helminthiasis model or the predicted equation was Y1 = 3.028 + 0.020 (elevation) – 2.098 (clay). For soil-transmitted helminthiasis, the mathematical model or the predicted equation was Y2 = −1.559 + 0.005 (rainfall) + 0.004 (elevation) − 2.198 (clay). The Ministry of Public Health has concluded that mass treatment for helminthiasis in the Thai population, targeting high-risk individuals, may be a cost-effective way to allocate limited funds. This type of approach, as well as further study on the correlation of clinical symptoms with environmental and geographic information, may offer a novel strategy to the helminth crisis.

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References

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Carlton, E.J., Liang, S., McDowell, J.Z., Li, H., Luo, W. & Remais, J.V. (2012) Regional disparities in the burden of disease attributable to unsafe water and poor sanitation in China. Bulletin of the World Health Organization 90, 578587.
Hotez, P.J., Molyneux, D.H., Fenwick, A., Kumaresan, J., Sachs, S.E., Sachs, J.D. & Savioli, L. (2007) Control of neglected tropical diseases. New England Journal of Medicine 6, 10181027.
Hotez, P.J., Brindley, P.J., Bethony, J.M., King, C.H., Pearce, E.J. & Jacobson, J. (2008) Helminth infections: the great neglected tropical diseases. Journal of Clinical Investigation 118, 13111321.
Jongsuksuntigul, P. & Imsomboon, T. (2003) Opisthorchiasis control in Thailand. Acta Tropica 88, 229232.
Jongsuksuntigul, P., Choeychomsri, W., Techamontrigul, P., Jerdit, P. & Suruthanavanith, P. (1992) Study on prevalence and intensity of intestinal helminthiasis and opisthorchiasis in Thailand. Journal of Tropical Medicine and Parasitology 15, 8095.
Levecke, B., Speybroeck, N., Dobson, R.J., Vercruysse, J. & Charlier, J. (2011) Novel insights in the fecal egg count reduction test for monitoring drug efficacy against soil-transmitted helminths in large-scale treatment programs. PLoS Neglected Tropical Diseases 5, 1427.
Levecke, B., Anderson, R.M., Berkvens, D., Charlier, J., Devleesschauwer, B., Speybroeck, N., Vercruysse, J. & Van, A.S. (2015) Mathematical inference on helminth egg counts in stool and its applications in mass drug administration programmes to control soil-transmitted helminthiasis in public health. Advanced Parasitology 87, 193247.
Nithikathkul, C. (2000) Liver flukes. Communicable Diseases Journal 26, 274278.
Nithikathkul, C., Sukthana, Y., Wongsawad, C., Nithikathkul, A., Nithikethkul, B., Wichmann, O., Gonzales, J.P., Hugot, J.G. & Herbreteau, V. (2008). Enterobiasis infection among Thai school children: spatial analysis using a geographic information system. Asian Biomedicine 2, 283288.
Rock, K.S., Rutte, E.A., Vlas, S.J., Adams, E.R., Medley, G.F. & Hollingsworth, T.D. (2015) Uniting mathematics and biology for control of visceral leishmaniasis. Trends in Parasitology 31, 251259.
Torgerson, P.R & Macpherson, C.N. (2011) The socioeconomic burden of parasitic zoonoses: global trends. Veterinary Parasitology 24, 7995.
Truscott, J., Hollingsworth, T.D. & Anderson, R. (2014) Modeling the interruption of the transmission of soil-transmitted helminth by repeated mass chemotherapy of school-age children. PLoS Neglected Tropical Diseases 8, 3323.
Wattanayingcharoenchai, S., Nithikathkul, C., Wongsaroj, T., Royal, L. & Reungsang, P. (2011) Geographic information system of Opisthorchis riverine in northeast Thailand. Asian Biomedicine 5, 687691.
WHO (World Health Organization). (2000) Global health estimates. Available at http://www.who.int/healthinfo/globalburdenDisease/en/ (accessed 10 October 2015).
WHO (World Health Organization). (2016) World Health Statistics 2016: Monitoring health for the SDGs. Report and annexes. Available at http://www.who.int/gho/en/ (accessed 16 July 2016).
Wongsaroj, T., Nithikathkul, C., Reungsang, P., Royal, L., Nakai, W., Krailas, D. & Ramasoota, P. (2012) Geographic information of helminthiasis in Thailand. International Journal of Geoinformatics 8, 5964.
Wongsaroj, T., Nithikathkul, C., Rojkitikul, W., Nakai, W., Royal, L. & Rammasut, P. (2014) National Survey of Helminthiasis in Thailand. Asian Biomedicine 8, 779783.

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