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Bacillus sphaericus interferes with the development of Brugia malayi in Aedes aegypti

  • N. Mahapatra (a1), R.K. Hazra (a2), S. Rup (a1), A.S Acharya (a1) and A.P. Dash (a2)...


Aedes aegypti (black-eyed Liverpool strain) were exposed to a sublethal dose (LD25) of Bacillus sphaericus and were fed to Mastomys coucha infected with Brugia malayi. The development of the filarial parasite was found to be arrested mostly at the second larval stage. The infection (P< 0.05), infectivity rates (P< 0.001) and L3 load (P< 0.001) were found to be reduced significantly in the treated group.


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Ewert, A. (1959) Comparative migration of microfilaria and development of Brugia pahangi in various mosquitoes. American Journal of Tropical Medicine and Hygiene 14, 245259.
Franz, M. & Zielke, E. (1980) Scanning electron microscope study on larvae of Wuchereria bancrofti from the vector and from experimental rodent hosts. Tropical Medicine and Parasitology 31, 345356.
Mohapatra, R., Ranjit, M.R. & Dash, A.P. (1996) The effect of chitin synthesis inhibitors on the development of Brugia malayi in Aedes aegypti. Journal of Helminthology 70, 269270.
Noireau, F. & Karch, S. (1983) Receptive a Plasmodium yoelii yoelii d' Anopheles soumis a Bacillus thuringiensis serotype H14 et Bacillus sphaericus. Cahiers ORSTOM Series Entomologie Médicale et Parasitologie 21, 221224.
Oda, T. & Wada, Y. (1980) Exsheathment and migration of microfilaria of Brugia malayi (Che-Ju strain) in mos-quitoes. Tropical Medicine 22, 278295.
Vilarinhos, P., de Tarso Ribeiro Maruniak, J.F. & Hall, D.W. (1996) Characterization and biological activity of a Brazilian isolate of Bacillus sphaericus (Weide) highly toxic to mosquito larvae. Memorias do Instituto Oswaldo Cruz 91, 771776.
Young, M.D., Undeen, H.A., Dame, D.A. & Wing, S.R. (1990) The effect of Bacillus sphaericus upon the susceptibility of Anopheles quadrimaculatus to Plasmodium berghei. Journal of the American Mosquito Control Association 6, 139145.


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