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Eosinophil cationic protein, specific IgE and IgG4 in human toxocariasis

Published online by Cambridge University Press:  08 March 2007

J.-F. Magnaval
Affiliation:
Department of Parasitology, CH Rangueil, University Hospitals, 31059 Toulouse 9, France
J.-H. Faufingue
Affiliation:
Department of Parasitology, CH Rangueil, University Hospitals, 31059 Toulouse 9, France
B. Morassin
Affiliation:
Department of Parasitology, CH Rangueil, University Hospitals, 31059 Toulouse 9, France
R. Fabre
Affiliation:
Department of Parasitology, CH Rangueil, University Hospitals, 31059 Toulouse 9, France
Corresponding
E-mail address:

Abstract

Among 67 French patients presenting a toxocaral infection, various demographic, environmental, clinical and laboratory parameters (blood eosinophil count, eosinophil cationic protein (ECP), serum total IgE, specific IgE against common inhalant allergens, specific IgE and IgG4 against Toxocara excretory-secretory antigens) were investigated. Correlation studies and logistic regression analyses were conducted, testing elevated levels of ECP, specific anti-Toxocara IgE or IgG4 as outcome variables An elevated ECP level was significantly associated with both cough and rhinitis, a high level of specific anti-Toxocara IgE with itchy rashes and possible atopic status, and an increase of specific anti-Toxocara IgG4 with rural residence.

Type
Research Article
Copyright
Copyright © Cambridge University Press 2006

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