1.Robinson, AM, Bucci, DJ. Physical exercise during pregnancy improves object recognition memory in adult offspring. Neuroscience. 2014; 256, 53–60.
2.Labonte-Lemoyne, E, Curnier, D, Ellemberg, D. Exercise during pregnancy enhances cerebral maturation in the newborn: a randomized controlled trial. J Clin Exp Neuropsychol. 2017; 39, 347–354.
3.Ferrari, N, Bae-Gartz, I, Bauer, C, et al. Exercise during pregnancy and its impact on mothers and offspring in humans and mice. J Dev Orig Health Dis. 2018; 9, 63–76.
4.Gomes da Silva, S, de Almeida, AA, Fernandes, J, et al. Maternal exercise during pregnancy increases BDNF levels and cell numbers in the hippocampal formation but not in the cerebral cortex of adult rat offspring. PLoS One. 2016; 11, e0147200.
5.Skaper, SD. Neurotrophic Factors: an overview. Methods Mol Biol. 2018; 1727, 1–17.
6.Solvsten, CAE, Daugaard, TF, Luo, Y, de Paoli, F, Christensen, JH, Nielsen, AL. The effects of voluntary physical exercise-activated neurotrophic signaling in rat hippocampus on mRNA levels of downstream signaling molecules. J Mol Neurosci. 2017; 62, 142–153.
7.Neeper, SA, Gomez-Pinilla, F, Choi, J, Cotman, CW. Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res. 1996; 726, 49–56.
8.Miki, T, Lee, KY, Yokoyama, T, et al. Differential effects of neonatal maternal separation on the expression of neurotrophic factors in rat brain. II: regional differences in the cerebellum versus the cerebral cortex. Okajimas Folia Anat Jpn. 2013; 90, 53–58.
9.Solvsten, CAE, de Paoli, F, Christensen, JH, Nielsen, AL. Voluntary physical exercise induces expression and epigenetic remodeling of VegfA in the rat hippocampus. Mol Neurobiol. 2018; 55, 567–582.
10.Tapia-Arancibia, L, Rage, F, Givalois, L, Arancibia, S. Physiology of BDNF: focus on hypothalamic function. Front Neuroendocrinol. 2004; 25, 77–107.
11.Yau, SY, Gil-Mohapel, J, Christie, BR, So, KF. Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? Biomed Res Int. 2014; 2014, 403120.
12.Arnardottir, NY, Koster, A, Domelen, DRV, et al. Association of change in brain structure to objectively measured physical activity and sedentary behavior in older adults: age, gene/environment susceptibility-Reykjavik study. Behav Brain Res. 2016; 296, 118–124.
13.Mayeur, S, Silhol, M, Moitrot, E, et al. Placental BDNF/TrkB signaling system is modulated by fetal growth disturbances in rat and human. Placenta. 2010; 31, 785–791.
14.Kawamura, K, Kawamura, N, Sato, W, Fukuda, J, Kumagai, J, Tanaka, T. Brain-derived neurotrophic factor promotes implantation and subsequent placental development by stimulating trophoblast cell growth and survival. Endocrinology. 2009; 150, 3774–3782.
15.Fowden, AL, Sferruzzi-Perri, AN, Coan, PM, Constancia, M, Burton, GJ. Placental efficiency and adaptation: endocrine regulation. J Physiol. 2009; 587, 3459–3472.
16.Dey, SK, Lim, H, Das, SK, et al. Molecular cues to implantation. Endocr Rev. 2004; 25, 341–373.
17.Jones, HN, Crombleholme, T, Habli, M. Adenoviral-mediated placental gene transfer of IGF-1 corrects placental insufficiency via enhanced placental glucose transport mechanisms. PLoS One. 2013; 8, e74632.
18.Clapp, JF, 3rd. The effects of maternal exercise on fetal oxygenation and feto-placental growth. Eur J Obstet Gynecol Reprod Biol. 2003; 110 Suppl1, S80–85.
19.Hsiao, EY, Patterson, PH. Placental regulation of maternal-fetal interactions and brain development. Dev Neurobiol. 2012; 72, 1317–1326.
20.Clapp, JF, 3rd, Kim, H, Burciu, B, Lopez, B. Beginning regular exercise in early pregnancy: effect on fetoplacental growth. Am J Obstet Gynecol. 2000; 183, 1484–1488.
21.Amorim, MF, dos Santos, JA, Hirabara, SM, et al. Can physical exercise during gestation attenuate the effects of a maternal perinatal low-protein diet on oxygen consumption in rats? Exp Physiol. 2009; 94, 906–913.
22.Du, MC, Ouyang, YQ, Nie, XF, Huang, Y, Redding, SR. Effects of physical exercise during pregnancy on maternal and infant outcomes in overweight and obese pregnant women: a meta-analysis. Birth. 2018; doi: 10.1111/birt.12396.
23.Davenport, MH, Meah, VL, Ruchat, SM, et al. Impact of prenatal exercise on neonatal and childhood outcomes: a systematic review and meta-analysis. Br J Sports Med. 2018; 52, 1386–1396.
24.Rosa, BV, Firth, EC, Blair, HT, Vickers, MH, Morel, PC. Voluntary exercise in pregnant rats positively influences fetal growth without initiating a maternal physiological stress response. Am J Physiol Regul Integr Comp Physiol. 2011; 300, R1134–1141.
25.Fragoso, J, Lira, AO, Chagas, GS, et al. Maternal voluntary physical activity attenuates delayed neurodevelopment in malnourished rats. Exp Physiol. 2017; 102, 1486–1499.
26.Santana Muniz, G, Beserra, R, da Silva Gde, P, et al. Active maternal phenotype is established before breeding and leads offspring to align growth trajectory outcomes and reflex ontogeny. Physiol Behav. 2014; 129, 1–10.
27.Knab, AM, Bowen, RS, Hamilton, AT, Gulledge, AA, Lightfoot, JT. Altered dopaminergic profiles: implications for the regulation of voluntary physical activity. Behav Brain Res. 2009; 204, 147–152.
28.Knab, AM, Bowen, RS, Hamilton, AT, Lightfoot, JT. Pharmacological manipulation of the dopaminergic system affects wheel-running activity in differentially active mice. J Biol Regul Homeost Agents. 2012; 26, 119–129.
29.Tsao, TS, Li, J, Chang, KS, et al. Metabolic adaptations in skeletal muscle overexpressing GLUT4: effects on muscle and physical activity. FASEB J. 2001; 15, 958–969.
30.Moore, T. Review: parent-offspring conflict and the control of placental function. Placenta. 2012; 33 (Suppl), S33–36.
31.Newcomer, SC, Taheripour, P, Bahls, M, et al. Impact of porcine maternal aerobic exercise training during pregnancy on endothelial cell function of offspring at birth. J Dev Orig Health Dis. 2012; 3, 4–9.
32.Wells, JC. The thrifty phenotype hypothesis: thrifty offspring or thrifty mother? J Theor Biol. 2003; 221, 143–161.
33.Ke, Z, Yip, SP, Li, L, Zheng, XX, Tong, KY. The effects of voluntary, involuntary, and forced exercises on brain-derived neurotrophic factor and motor function recovery: a rat brain ischemia model. PLoS One. 2011; 6, e16643.
34.De Assis, GG, Gasanov, EV, de Sousa, MBC, Kozacz, A, Murawska-Cialowicz, E. Brain derived neutrophic factor, a link of aerobic metabolism to neuroplasticity. J Physiol Pharmacol. 2018; 69, 351–358.
35.Kim, P, Strathearn, L, Swain, JE. The maternal brain and its plasticity in humans. Horm Behav. 2016; 77, 113–123.
36.Wessels, JM, Leyland, NA, Agarwal, SK, Foster, WG. Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors. Hum Reprod. 2015; 30, 925–936.
37.Antonio-Santos, J, Ferreira, DJ, Gomes Costa, GL, et al. Resistance training alters the proportion of skeletal muscle fibers but not brain neurotrophic factors in young adult rats. J Strength Cond Res. 2016; 30, 3531–3538.
38.Leasure, JL, Jones, M. Forced and voluntary exercise differentially affect brain and behavior. Neuroscience. 2008; 156, 456–465.
39.Fernandez, C, Tatard, VM, Bertrand, N, Dahmane, N. Differential modulation of sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network. Dev Neurosci. 2010; 32, 59–70.
40.Anderson, MF, Aberg, MA, Nilsson, M, Eriksson, PS. Insulin-like growth factor-I and neurogenesis in the adult mammalian brain. Brain Res Dev Brain Res. 2002; 134, 115–122.
41.Llorens-Martin, M, Torres-Aleman, I, Trejo, JL. Growth factors as mediators of exercise actions on the brain. Neuromolecular Med. 2008; 10, 99–107.
42.Wells, JCK. Life history trade-offs and the partitioning of maternal investment: implications for health of mothers and offspring. Evol Med Public Health. 2018; 2018, 153–166.
43.Rebelato, HJ, Esquisatto, MA, Moraes, C, Amaral, ME, Catisti, R. Gestational protein restriction induces alterations in placental morphology and mitochondrial function in rats during late pregnancy. J Mol Histol. 2013; 44, 629–637.
44.Manokhina, I, Del Gobbo, GF, Konwar, C, Wilson, SL, Robinson, WP. Review: placental biomarkers for assessing fetal health. Hum Mol Genet. 2017; 26, R237–R245.