Barker, DJ. Adult consequences of fetal growth restriction. Clin Obstet Gynecol. 2006; 49, 270–283.
Hanson, MA, Gluckman, PD. Developmental origins of health and disease: moving from biological concepts to interventions and policy. Int J Gynaecol Obstet. 2011; 115, S3–S5.
Ong, KK. Catch-up growth in small for gestational age babies: good or bad?
Curr Opin Endocrinol Diabetes Obes. 2007; 14, 30–34.
Hofman, PL, Cutfield, WS, Robinson, EM, et al. Insulin resistance in short children with intrauterine growth retardation. J Clin Endocrinol Metab. 1997; 82, 402–406.
Kass, SU, Pruss, D, Wolffe, AP. How does DNA methylation repress transcription?
Trends Genet. 1997; 13, 444–449.
Gordon, L, Joo, JE, Powell, JE, et al. Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res. 2012; 22, 1395–1406.
Fu, Q, Yu, X, Callaway, CW, Lane, RH, McKnight, RA. Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene. FASEB J. 2009; 23, 2438–2449.
Lillycrop, KA, Phillips, ES, Torrens, C, et al. Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPAR alpha promoter of the offspring. Br J Nutr. 2008; 100, 278–282.
Burdge, GC, Lillycrop, KA, Phillips, ES, et al. Folic acid supplementation during the juvenile-pubertal period in rats modifies the phenotype and epigenotype induced by prenatal nutrition. J Nutr. 2009; 139, 1054–1060.
Zeng, Y, Gu, P, Liu, K, Huang, P. Maternal protein restriction in rats leads to reduced PGC-1alpha expression via altered DNA methylation in skeletal muscle. Mol Med Rep. 2012; 7, 306–312.
Wallace, JM, Luther, JS, Milne, JS, et al. Nutritional modulation of adolescent pregnancy outcome – a review. Placenta. 2006; 27, S61–S68.
Wallace, JM, Milne, JS, Matsuzaki, M, Aitken, RP. Serial measurement of uterine blood flow from mid to late gestation in growth restricted pregnancies induced by overnourishing adolescent sheep dams. Placenta. 2008; 8, 718–724.
Wallace, JM, Milne, JS, Aitken, RP, Hay, WW. Sensitivity to metabolic signals in late-gestation growth-restricted fetuses from rapidly growing adolescent sheep. Am J Physiol Endocrinol Metab. 2007; 293, E1233–E1241.
Wallace, JM, Regnault, TR, Limesand, SW, Hay, WW, Anthony, RV. Investigating the causes of low birth weight in contrasting ovine paradigms. J Physiol. 2005; 565, 19–26.
Wallace, JM, Aitken, RP, Milne, JS, Hay, WW. Nutritionally mediated placental growth restriction in the growing adolescent: consequences for the fetus. Biol Reprod. 2004; 4, 1055–1062.
Wallace, JM, Milne, JS, Aitken, RP, Adam, CL. Impact of embryo donor adiposity, birth weight and gender on early postnatal growth, glucose metabolism and body composition in the young lamb. Reprod Fertil Dev. 2014; 26, 665–681.
Begum, G, Stevens, A, Smith, EB, et al. Epigenetic changes in fetal hypothalamic energy regulating pathways are associated with maternal undernutrition and twinning. FASEB J. 2012; 26, 1694–1703.
Lan, X, Cretney, EC, Kropp, J, et al. Maternal diet during pregnancy induces gene expression and DNA methylation changes in fetal tissues in sheep. Front Genet. 2013; 4, 49.
Wallace, JM, Bourke, DA, Aitken, RP, et al. Relationship between nutritionally-mediated placental growth restriction and fetal growth, body composition and endocrine status during late gestation in adolescent sheep. Placenta. 2000; 21, 100–108.
Wallace, JM, Da Silva, P, Aitken, RP, Cruickshank, MA. Maternal endocrine status in relation to pregnancy outcome in rapidly growing adolescent sheep. J Endocrinol. 1997; 155, 359–368.
Wallace, JM, Milne, JS, Redmer, DA, Aitken, RP. Effect of diet composition on pregnancy outcome in overnourished rapidly growing adolescent sheep. Br J Nutr. 2006; 96, 1060–1068.
Wallace, JM, Aitken, RP, Cheyne, MA. Nutrient partitioning and fetal growth in rapidly growing adolescent ewes. J Reprod Fertil. 1996; 107, 183–190.
Wallace, JM, Milne, JS, Aitken, RP. Effect of weight and adiposity at conception and wide variations in gestational dietary intake on pregnancy outcome and early postnatal performance in young adolescent sheep. Biol Reprod. 2010; 82, 320–330.
Umetani, N, de Maat, MF, Mori, T, Takeuchi, H, Hoon, DS. Synthesis of universal unmethylated control DNA by nested whole genome amplification with phi29 DNA polymerase. Biochem Biophys Res Commun. 2005; 329, 219–223.
Gao, ZH, Suppola, S, Liu, J, et al. Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors. J Clin Endocrinol Metab. 2002; 87, 1170–1176.
Gluckman, PD, Hanson, MA. Maternal constraint of fetal growth and its consequences. Semin Fetal Neonatal Med. 2004; 9, 419–425.
Ludwig, T, Eggenschwiler, J, Fisher, P, et al. Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds. Dev Biol. 1996; 177, 517–535.
Turner, CL, Mackay, DM, Callaway, JL, et al. Methylation analysis of 79 patients with growth restriction reveals novel patterns of methylation change at imprinted loci. Eur J Hum Genet. 2010; 18, 648–655.
Adams, TE. Differential expression of growth hormone receptor messenger RNA from a second promoter. Mol Cell Endocrinol. 1995; 108, 23–33.
Begum, G, Davies, A, Stevens, A, et al. Maternal undernutrition programs tissue-specific epigenetic changes in the glucocorticoid receptor in adult offspring. Endocrinology. 2013; 154, 4560–4569.
Carr, DJ, Aitken, RP, Milne, JS, David, AL, Wallace, JM. Fetoplacental biometry and umbilical artery Doppler velocimetry in the overnourished adolescent model of fetal growth restriction. Am J Obstet Gynecol. 2012; 207, 141.e6–141.e15.
Heijmans, BT, Tobi, EW, Stein, AD, et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci USA. 2008; 105, 17046–17049.
Tobi, EW, Lumey, LH, Talens, RP, et al. DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet. 2009; 18, 4046–4053.
Tobi, EW, Heijmans, BT, Kremer, D, et al. DNA methylation of IGF2, GNASAS, INSIGF and LEP and being born small for gestational age. Epigenetics. 2011; 6, 171–176.
Munshi, A, Shafi, G, Aliya, N, Jyothy, A. Histone modifications dictate specific biological readouts. J Genet Genomics. 2009; 36, 75–88.
Chuang, JC, Jones, PA. Epigenetics and microRNAs. Pediatr Res. 2007; 61, 24R–29R.
Ke, X, Schober, ME, McKnight, RA, et al. Intrauterine growth retardation affects expression and epigenetic characteristics of the rat hippocampal glucocorticoid receptor gene. Physiol Genomics. 2010; 42, 177–189.
Joss-Moore, LA, Wang, Y, Baack, ML, et al. IUGR decreases PPARgamma and SETD8 expression in neonatal rat lung and these effects are ameliorated by maternal DHA supplementation. Early Hum Dev. 2010; 86, 785–791.
Joss-Moore, LA, Wang, Y, Ogata, EM, et al. IUGR differentially alters MeCP2 expression and H3K9Me3 of the PPARgamma gene in male and female rat lungs during alveolarization. Birth Defects Res A Clin Mol Teratol. 2011; 91, 672–681.
Gatford, KL, Simmons, RA. Prenatal programming of insulin secretion in intrauterine growth restriction. Clin Obstet Gynecol. 2013; 56, 520–528.
Ritz, E, Amann, K, Koleganova, N, Benz, K. Prenatal programming-effects on blood pressure and renal function. Nat Rev Nephrol. 2011; 7, 137–144.
Boguszewski, MC, Johannsson, G, Fortes, LC, Sverrisdottir, YB. Low birth size and final height predict high sympathetic nerve activity in adulthood. J Hypertens. 2004; 22, 1157–1163.
Hall, E, Volkov, P, Dayeh, T, et al. Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets. Genome Biol. 2014; 15, 522.
Gu, T, Gu, HF, Hilding, A, Ostenson, CG, Brismar, K. DNA methylation analysis of the insulin-like growth factor-1 (IGF1) gene in Swedish men with normal glucose tolerance and type 2 diabetes. J Diabetes Metab. 2014; 5, 1000419.
Dickson, MC, Saunders, JC, Gilmour, RS. The ovine insulin-like growth factor-I gene: characterization, expression and identification of a putative promoter. J Mol Endocrinol. 1991; 6, 17–31.
Ohlsen, SM, Dean, DM, Wong, EA. Characterization of multiple transcription initiation sites of the ovine insulin-like growth factor-I gene and expression profiles of three alternatively spliced transcripts. DNA Cell Biol. 1993; 12, 243–251.
Maunakea, AK, Chepelev, I, Cui, K, Zhao, K. Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition. Cell Res. 2013; 23, 1256–1269.
Nikoshkov, A, Sunkari, V, Savu, O, et al. Epigenetic DNA methylation in the promoters of the Igf1 receptor and insulin receptor genes in db/db mice. Epigenetics. 2011; 6, 405–409.
El-Maarri, O, Becker, T, Junen, J, et al. Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males. Hum Genet. 2007; 122, 505–514.
Callewaert, F, Sinnesael, M, Gielen, E, Boonen, S, Vanderschueren, D. Skeletal sexual dimorphism: relative contribution of sex steroids, GH-IGF1, and mechanical loading. J Endocrinol. 2010; 207, 127–134.
Fukuda, R, Usuki, S, Mukai, N, et al. Serum insulin-like growth factor-I, insulin-like growth factor binding protein-3, sex steroids, osteocalcin and bone mineral density in male and female rats. Gynecol Endocrinol. 1998; 12, 297–305.
Xu, S, Gu, X, Pan, H, et al. Reference ranges for serum IGF-1 and IGFBP-3 levels in Chinese children during childhood and adolescence. Endocr J. 2010; 57, 221–228.
Gatford, KL, Heinemann, GK, Thompson, SD, et al. Circulating IGF1 and IGF2 and SNP genotypes in men and pregnant and non-pregnant women. Endocr Connect. 2014; 3, 138–149.
Taekema, DG, Ling, CH, Blauw, GJ, et al. Circulating levels of IGF1 are associated with muscle strength in middle-aged- and oldest-old women. Eur J Endocrinol. 2011; 164, 189–196.
Wallace, JM, Milne, JS, Adam, CL, Aitken, RP. Adverse metabolic phenotype in low-birth-weight lambs and its modification by postnatal nutrition. Br J Nutr. 2012; 107, 510–522.
Tsai, HW, Grant, PA, Rissman, EF. Sex differences in histone modifications in the neonatal mouse brain. Epigenetics. 2009; 4, 47–53.
Sharma, S, Eghbali, M. Influence of sex differences on microRNA gene regulation in disease. Biol Sex Differ. 2014; 5, 1–8.
Meinhardt, UJ, Ho, KKY. Modulation of growth hormone action by sex steroids. Clin Endocrinol. 2006; 65, 413–422.
Chowen, JA, Frago, LM, Argente, J. The regulation of GH secretion by sex steroids. Eur J Endocrinol. 2004; 151, U95–U100.
Ramirez, MC, Bourguignon, NS, Bonaventura, MM, et al. Neonatal xenoestrogen exposure alters growth hormone-dependent liver proteins and genes in adult female rats. Toxicol Lett. 2012; 213, 325–331.
Ho, KK, Gibney, J, Johannsson, G, Wolthers, T. Regulating of growth hormone sensitivity by sex steroids: implications for therapy. Front Horm Res. 2006; 35, 115–128.
Wang, J, Tang, J, Lai, M, Zhang, H. 5-Hydroxymethylcytosine and disease. Mutat Res Rev Mutat Res. 2014; 762, 167–175.
Sinclair, KD, Allegrucci, C, Singh, R, et al. DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. Proc Natl Acad Sci USA. 2007; 104, 19351–19356.
Wang, KC, Zhang, L, McMillen, IC, et al. Fetal growth restriction and the programming of heart growth and cardiac insulin-like growth factor 2 expression in the lamb. J Physiol. 2011; 589, 4709–4722.
Market-Velker, BA, Zhang, L, Magri, LS, Bonvissuto, AC, Mann, MR. Dual effects of superovulation: loss of maternal and paternal imprinted methylation in a dose-dependent manner. Hum Mol Genet. 2010; 19, 36–51.
Fortier, AL, McGraw, S, Lopes, FL, et al. Modulation of imprinted gene expression following superovulation. Mol Cell Endocrinol. 2014; 388, 51–57.
Herzog, E, Galvez, J, Roks, A, et al. Tissue-specific DNA methylation profiles in newborns. Clin Epigenetics. 2013; 5, 8.
Tosh, DN, Fu, Q, Callaway, CW, et al. Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth. Am J Physiol Gastrointest Liver Physiol. 2010; 299, G1023–G1029.
Lim, K, Armitage, JA, Stefanidis, A, Oldfield, BJ, Black, MJ. IUGR in the absence of postnatal ‘catch-up’ growth leads to improved whole body insulin sensitivity in rat offspring. Pediatr Res. 2011; 70, 339–344.
McGrattan, PD, Wylie, AR, Bjourson, AJ. A partial cDNA sequence of the ovine insulin receptor gene: evidence for alternative splicing of an exon 11 region and for tissue-specific regulation of receptor isoform expression in sheep muscle, adipose tissue and liver. J Endocrinol. 1998; 159, 381–387.