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Growth from birth to 6 months of infants with and without intrauterine preeclampsia exposure

Published online by Cambridge University Press:  12 May 2021

Megan L. Gow Open the ORCID record for Megan L. Gow [Opens in a new window] ,
Lynne Roberts ,
Amanda Henry ,
Gregory Davis ,
George Mangos ,
Franziska Pettit ,
Joseph M. Khouri ,
Ana Dosen ,
Mark A. Brown  and
Maria E. Craig
Megan L. Gow*
Affiliation:
Women’s and Children’s Health, St George Hospital, Sydney, Australia University of Sydney Children’s Hospital Westmead Clinical School, Sydney, Australia School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia
Lynne Roberts
Affiliation:
Women’s and Children’s Health, St George Hospital, Sydney, Australia St George and Sutherland Clinical School, University of New South Wales, Sydney, Australia
Amanda Henry
Affiliation:
Women’s and Children’s Health, St George Hospital, Sydney, Australia School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia The George Institute for Global Health, Sydney, Australia
Gregory Davis
Affiliation:
Women’s and Children’s Health, St George Hospital, Sydney, Australia School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia
George Mangos
Affiliation:
St George and Sutherland Clinical School, University of New South Wales, Sydney, Australia Renal Medicine, St George Hospital, Sydney, Australia
Franziska Pettit
Affiliation:
St George and Sutherland Clinical School, University of New South Wales, Sydney, Australia Renal Medicine, St George Hospital, Sydney, Australia
Joseph M. Khouri
Affiliation:
School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia
Ana Dosen
Affiliation:
School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia
Mark A. Brown
Affiliation:
St George and Sutherland Clinical School, University of New South Wales, Sydney, Australia Renal Medicine, St George Hospital, Sydney, Australia
Maria E. Craig
Affiliation:
Women’s and Children’s Health, St George Hospital, Sydney, Australia University of Sydney Children’s Hospital Westmead Clinical School, Sydney, Australia School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia
*
Address for correspondence: Megan L. Gow, Women’s and Children’s Health, St George HospitalSydney, NSW2217, Australia. Email: megan.gow@health.nsw.gov.au
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Abstract

Intrauterine preeclampsia exposure affects the lifelong cardiometabolic health of the child. Our study aimed to compare the growth (from birth to 6 months) of infants exposed to either a normotensive pregnancy or preeclampsia and explore the influence of being born small for gestational age (SGA). Participants were children of women participating in the Post-partum, Physiology, Psychology and Paediatric follow-up cohort study. Birth and 6-month weight and length z-scores were calculated for term and preterm (<37 weeks) babies, and change in weight z-score, rapid weight gain (≥0.67 increase in weight z-score) and conditional weight gain z-score were calculated. Compared with normotensive exposed infants (n = 298), preeclampsia exposed infants (n = 84) were more likely to be born SGA (7% versus 23%; P < 0.001), but weight gain from birth to 6 months, by any measure, did not differ between groups. Infants born SGA, irrespective of pregnancy exposure, were more likely to have rapid weight gain and had greater increases in weight z-score compared with those not born SGA. Preeclampsia exposed infants born SGA may benefit from interventions designed to prevent future cardiometabolic disease.

Keywords

Growthinfantspreeclampsiasmall for gestational age
Type
Brief Reports
Information
Journal of Developmental Origins of Health and Disease , Volume 13 , Issue 2 , April 2022 , pp. 151 - 155
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Copyright
© The Author(s), 2021. Published by Cambridge University Press in association with International Society for Developmental Origins of Health and Disease

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References

Payne, B, Hanson, C, Sharma, S, Magee, L, Von Dadelszen, P. Chapter 4: Epidemiology of the hypertensive disorders of pregnancy. In The FIGO Textbook of Pregnancy Hypertension: An Evidence-Based Guide To Monitoring, Prevention and Management (eds. Magee, L, Von Dadelszen, P, Stones, W, Matthews, M), 2016; pp. 63–74. The Global Library of Women’s Medicine, Carlisle, UK.Google Scholar
Brown, MC, Best, KE, Pearce, MS, Waugh, J, Robson, SC, Bell, R. Cardiovascular disease risk in women with pre-eclampsia: systematic review and meta-analysis. Eur J Epidemiol. 2013; 28(1), 1–19.CrossRefGoogle ScholarPubMed
Theilen, LH, Fraser, A, Hollingshaus, MS, et al. All-cause and cause-specific mortality after hypertensive disease of pregnancy. Obstet Gynecol. 2016; 128(2), 238–244.10.1097/AOG.0000000000001534CrossRefGoogle ScholarPubMed
Duley, L. The global impact of pre-eclampsia and eclampsia. Semin Perinatol. 2009; 33(3), 130–137.CrossRefGoogle ScholarPubMed
Steegers, EA, von Dadelszen, P, Duvekot, JJ, Pijnenborg, R. Pre-eclampsia. Lancet. 2010; 376(9741), 631–644.CrossRefGoogle ScholarPubMed
Davis, EF, Lazdam, M, Lewandowski, AJ, et al. Cardiovascular risk factors in children and young adults born to preeclamptic pregnancies: a systematic review. Pediatrics. 2012; 129(6), e1552–e1561.CrossRefGoogle Scholar
Nahum Sacks, K, Friger, M, Shoham-Vardi, I, et al. Prenatal exposure to preeclampsia as an independent risk factor for long-term cardiovascular morbidity of the offspring. Pregnancy Hypertens. 2018; 13, 181–186.CrossRefGoogle ScholarPubMed
Pinheiro, TV, Brunetto, S, Ramos, JG, Bernardi, JR, Goldani, MZ. Hypertensive disorders during pregnancy and health outcomes in the offspring: a systematic review. J Dev Orig Health Dis. 2016; 7(4), 391–407.10.1017/S2040174416000209CrossRefGoogle ScholarPubMed
Maher, GM, O’Keeffe, GW, Dalman, C, et al. Association between preeclampsia and autism spectrum disorder: a population-based study. J Child Psychol Psychiatry. 2020; 61(2), 131–139.CrossRefGoogle ScholarPubMed
Nahum Sacks, K, Friger, M, Shoham-Vardi, I, et al. Long-term neuropsychiatric morbidity in children exposed prenatally to preeclampsia. Early Hum Dev. 2019; 130, 96–100.CrossRefGoogle ScholarPubMed
Tzoulaki, I, Sovio, U, Pillas, D, et al. Relation of immediate postnatal growth with obesity and related metabolic risk factors in adulthood: the northern Finland birth cohort 1966 study. Am J Epidemiol. 2010; 171(9), 989–998.CrossRefGoogle ScholarPubMed
Barker, DJ, Gluckman, PD, Godfrey, KM, Harding, JE, Owens, JA, Robinson, JS. Fetal nutrition and cardiovascular disease in adult life. Lancet. 1993; 341(8850), 938–941.10.1016/0140-6736(93)91224-ACrossRefGoogle ScholarPubMed
Gunnarsdottir, J, Cnattingius, S, Lundgren, M, Selling, K, Hogberg, U, Wikstrom, AK. Prenatal exposure to preeclampsia is associated with accelerated height gain in early childhood. PLoS One. 2018; 13(2), e0192514.CrossRefGoogle ScholarPubMed
Davis, GK, Roberts, L, Mangos, G, et al. Postpartum physiology, psychology and paediatric follow up study (P4 Study) - Study protocol. Pregnancy Hypertens. 2016; 6(4), 374–379.CrossRefGoogle ScholarPubMed
Brown, MA, Roberts, L, Hoffman, A, et al. Recognising cardiovascular risk after pre-eclampsia: the P4 study. J Am Heart Assoc. 2020; 9(22), e018604.10.1161/JAHA.120.018604CrossRefGoogle Scholar
Brown, MA, Magee, LA, Kenny, LC, et al. The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice. Pregnancy Hypertens. 2018; 13, 291–310.CrossRefGoogle ScholarPubMed
Villar, J, Giuliani, F, Bhutta, ZA, et al. Postnatal growth standards for preterm infants: the Preterm Postnatal Follow-up Study of the INTERGROWTH-21(st) Project. Lancet Glob Health. 2015; 3(11), e681–e691.CrossRefGoogle ScholarPubMed
Cole, TJ, Freeman, JV, Preece, MA. British 1990 growth reference centiles for weight, height, body mass index and head circumference fitted by maximum penalized likelihood. Stat Med. 1998; 17(4), 407–429.3.0.CO;2-L>CrossRefGoogle ScholarPubMed
World Health Organisation Multicentre Growth Reference Study Group. WHO Child Growth Standards: Length/Height-for-age, Weight-for-age, Weight-for-length, Weight-for-height and Body Mass Index-for age. 2006; WHO, Geneva, Switzerland.Google Scholar
de Onis, M, Habicht, JP. Anthropometric reference data for international use: recommendations from a World Health Organization Expert Committee. Am J Clin Nutr. 1996; 64(4), 650–658.CrossRefGoogle ScholarPubMed
Report of a WHO Expert Committee. Physical status: the use and interpretation of anthropometry. World Health Organ Tech Rep Ser. 1995; 854, 1–452.Google Scholar
Ong, KK, Loos, RJ. Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions. Acta Paediatr. 2006; 95(8), 904–908.CrossRefGoogle ScholarPubMed
Cole, TJ. Conditional reference charts to assess weight gain in British infants. Arch Dis Child. 1995; 73(1), 8–16.CrossRefGoogle ScholarPubMed
Cole, TJ. Presenting information on growth distance and conditional velocity in one chart: practical issues of chart design. Stat Med. 1998; 17(23), 2697–2707.10.1002/(SICI)1097-0258(19981215)17:23<2697::AID-SIM36>3.0.CO;2-O3.0.CO;2-O>CrossRefGoogle ScholarPubMed
Griffiths, LJ, Smeeth, L, Hawkins, SS, Cole, TJ, Dezateux, C. Effects of infant feeding practice on weight gain from birth to 3 years. Arch Dis Child. 2009; 94(8), 577–582.CrossRefGoogle ScholarPubMed
Paul, IM, Savage, JS, Anzman, SL, et al. Preventing obesity during infancy: a pilot study. Obesity (Silver Spring). 2011; 19(2), 353–361.CrossRefGoogle ScholarPubMed
Huang, Y, Zhang, W, Go, K, et al. Altered growth trajectory in children born to mothers with gestational diabetes mellitus and preeclampsia. Arch Gynecol Obstet. 2020; 301(1), 151–159.CrossRefGoogle ScholarPubMed
Woo, JG. Infant growth and long-term cardiometabolic health: a review of recent findings. Curr Nutr Rep. 2019; 8(1), 29–41.CrossRefGoogle ScholarPubMed
Byberg, KK, Oymar, K, Eide, GE, Forman, MR, Juliusson, PB. Exposure to preeclampsia in utero affects growth from birth to late childhood dependent on child’s sex and severity of exposure: follow-up of a nested case-control study. PLoS One. 2017; 12(5), e0176627.CrossRefGoogle ScholarPubMed
Wang, LB, Qu, B, Xu, P, et al. Preeclampsia exposed offspring have greater body mass index than non-exposed offspring during peripubertal life: a meta-analysis. Pregnancy Hypertens. 2020; 19, 247–252.CrossRefGoogle ScholarPubMed