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Mild protein hydrolysation of lactose-free milk further reduces milk-related gastrointestinal symptoms

Published online by Cambridge University Press:  01 April 2016

Anu Turpeinen ,
Hanna Kautiainen ,
Marja-Leena Tikkanen ,
Timo Sibakov ,
Olli Tossavainen  and
Eveliina Myllyluoma
Anu Turpeinen*
Affiliation:
Valio Ltd, R&D, P.O. Box 30, 00039 Valio, Finland
Hanna Kautiainen
Affiliation:
Valio Ltd, R&D, P.O. Box 30, 00039 Valio, Finland
Marja-Leena Tikkanen
Affiliation:
Valio Ltd, R&D, P.O. Box 30, 00039 Valio, Finland
Timo Sibakov
Affiliation:
Valio Ltd, R&D, P.O. Box 30, 00039 Valio, Finland
Olli Tossavainen
Affiliation:
Valio Ltd, R&D, P.O. Box 30, 00039 Valio, Finland
Eveliina Myllyluoma
Affiliation:
Valio Ltd, R&D, P.O. Box 30, 00039 Valio, Finland
*
*For correspondence; e-mail: anu.turpeinen@valio.fi
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Abstract

Gastrointestinal symptoms associated with milk are common. Besides lactose, milk proteins may cause symptoms in sensitive individuals. We have developed a method for mild enzymatic hydrolysation of milk proteins and studied the effects of hydrolysed milk on gastrointestinal symptoms in adults with a self-diagnosed sensitive stomach. In a double blind, randomised placebo-controlled study, 97 subjects consumed protein-hydrolysed lactose-free milk or commercially available lactose-free milk for 10 d. Frequency of gastrointestinal symptoms during the study period was reported and a symptom score was calculated. Rumbling and flatulence decreased significantly in the hydrolysed milk group (P < 0·05). Also, the total symptom score was lower in subjects who consumed hydrolysed milk (P < 0·05). No difference between groups was seen in abdominal pain (P = 0·47) or bloating (P = 0·076). The results suggest that mild enzymatic protein hydrolysation may decrease gastrointestinal symptoms in adults with a sensitive stomach.

Keywords

Milk proteinenzymatic hydrolysationgastrointestinal symptomshuman
Type
Research Article
Information
Journal of Dairy Research , Volume 83 , Issue 2 , May 2016 , pp. 256 - 260
Copyright
Copyright © Proprietors of Journal of Dairy Research 2016 

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