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Evaluation of the serum fructosamine test to monitor plasma glucose concentration in the transition dairy cow

Published online by Cambridge University Press:  05 January 2009

María L Sorondo  and
Alberto Cirio
María L Sorondo
Affiliation:
Departamento de Patología y Clínica de Rumiantes y Suinos, Alberto Lasplaces 1550, Montevideo 11600, Uruguay
Alberto Cirio*
Affiliation:
Departamento de Fisiología, Facultad de Veterinaria, Alberto Lasplaces 1550, Montevideo 11600, Uruguay
*
*For correspondence; e-mail: albertocirio@yahoo.com
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Abstract

The usefulness of the serum fructosamine (Fser) to monitor the retrospective glucose concentrations in transitional dairy cows (n=17) was evaluated. In weekly blood samples (3 weeks before to 5 weeks after calving) concentrations of plasma glucose and serum fructosamine, β-hydroxybutyrate (βOHB) and total proteins were determined. The observed Fser concentrations (271±55 mean value, range 152–423 μmol/l) were within the range reported in the literature, and showed a progressive and significant decrease after calving. Mean plasma glucose concentration was 60·6±5·0 (range 39·9–82·2) mg/dl increasing from week 3 before calving to the week of calving and then decreasing during the next 5 weeks of lactation. This decrease was coincident with inverse relationships between plasma glucose and milk yield (P=0·03) and serum βOHB (P<0·001). Linear regression analysis performed between serum fructosamine and (a) plasma glucose concentration of the same sampling and (b) plasma glucose concentration of 1, 2 and 3 weeks preceding the sampling, did not show significant and systematizing positive correlations. Persistent hypoproteinaemias that could affect the fructosamine concentrations were not found: mean value and range of serum proteins was 6·3±1·0 and 4·8–7·8 g/dl, respectively, and no correlation was found between serum proteins and Fser (P=0·26). Results did not support the possibility of retrospective monitoring of the plasma glucose concentration by serum fructosamine in dairy cows in the transition period.

Keywords

Serum fructosamineplasma glucosedairy cowtransition period
Type
Research Article
Information
Journal of Dairy Research , Volume 76 , Issue 2 , May 2009 , pp. 173 - 178
Copyright
Copyright © Proprietors of Journal of Dairy Research 2008

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