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Fractional rate of protein synthesis in liver and in individual muscles of lambs: effect of time of sampling following the use of the continuous infusion technique

Published online by Cambridge University Press:  27 March 2009

R. A. Hunter
Affiliation:
Department of Applied Biochemistry and Food Science, University of Nottingham, Sutton Bonington, Loughborough
Jane B. Davey
Affiliation:
Department of Applied Biochemistry and Food Science, University of Nottingham, Sutton Bonington, Loughborough
P. J. Buttery
Affiliation:
Department of Applied Biochemistry and Food Science, University of Nottingham, Sutton Bonington, Loughborough

Extract

There is little information on rates of protein synthesis in individual muscles in ruminant animals. Skeletal muscle is the largest single tissue and, as such, has a considerable effect on nitrogen transactions in the body. Arnal (1977) found a substantial decline in synthetic rate between 1 and 16 weeks of age in lambs and also observed differences between red and white muscles. Bryant & Smith (1982a) measured synthesis in several muscles of mature sheep and they observed lower rates than Arnal (1977) with little difference between most muscles. Vastus intermedius muscle in the hind leg, however, had higher rates of synthesis than other muscles. Here we report rates of protein synthesis in individual muscles in rapidly growing lambs approximately 12 weeks of age. The major back muscle, the longissimus dorsi, and two hind leg muscles, the vastus lateralis and the vastus intermedius, were chosen for study.

Type
Short Notes
Copyright
Copyright © Cambridge University Press 1987

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