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Opiate dependence in acute intermittent porphyria

Published online by Cambridge University Press:  13 June 2014

Immanuel P McKenzie
Affiliation:
The Harrogate Child, Adolescent and Family Service, Dragon Parade Clinic, 2 Dragon Parade, Harrogate, HG1 2BY, England

Abstract

Acute Intermittent Porphyria (AIP) is often accompanied by psychiatric disturbance. Despite routine use of opiate analgesia in the treatment of the acute illness, only one case of dependence is described in the literature. We report a further case where dependence on morphine complicated the assessment and management of a woman with AIP who had been admitted to psychiatric hospital following the death of her child. Clinical implications are discussed.

Type
Brief Reports
Copyright
Copyright © Cambridge University Press 1994

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References

1.Goldberg, A, Rimington, C. Diseases of porphyria metabolism. Spring-field IL; Charles C. Thomas, 1962.Google Scholar
2.Kappas, A, Sassa, S, Anderson, KE. The porphyrias. In: the metabolic basis of inherited disease. Stanbury, JB, Wyngaarden, JB, Frederickson, DS, editors. New York: Mcgraw-Hill, 1983.Google Scholar
3.Goldberg, L, Stinnett, J. AIP in Schizophrenics. Penn Med 1983; 86(4): 52–3.Google Scholar
4.Lempiere, T, Moreaux, C. Mental status of porphyriac patients between acute attacks. Annals of Medical Psychology (Paris), 1979; 137(1-2): 120–9.Google Scholar
5.Roth, N. The psychiatric syndromes of porphyria. Int J Neuropsychiatr 1968; 4(1): 32–4.Google ScholarPubMed
6.Grabowski, J, Yeragani, V. Porphyria and psychosis: a case report. Can J Psychiatr, 1987; 32(5): 383–4.CrossRefGoogle ScholarPubMed
7.Morse, RH. Porphyria and pain management. Journal of L.A State Medical Society, 1984; 136(8): 15–8.Google ScholarPubMed
8.Lishman, WA. Organic Psychiatry. Oxford: Blackwell Scientific Publications, 1987.Google Scholar
9.Ackner, B, Cooper, JE, Gray, CH, Kelly, M. Acute porphyria: a neuro-psychiatric and biochemical study. J Psychosom Res 1962; 6: 124.CrossRefGoogle Scholar
10.Moore, MR, Disler, PB. Drug-sensitive diseases – 1: Acute porphyrias. Adverse Drug Reaction Bulletin, 1988; 129: 484–7.CrossRefGoogle Scholar