Anderson, AE, Marder, S, Reise, SP, Savitz, A, Salvadore, G, Fu, DJ, Li, Q, Turkoz, I, Han, C, Bilder, RM (2018). Bifactor modeling of the Positive and Negative Syndrome Scale: generalized psychosis spans schizoaffective, bipolar and schizophrenia diagnoses. Schizophrenia Bulletin 44, 1204–1216. doi: 10.1093/schbul/sbx163.
Arango, C, Diaz-Caneja, CM, McGorry, PD, Rapoport, J, Sommer, IE, Vorstman, JA, McDaid, D, Marion, O, Serrano-Drozdowskyj, E, Freedman, R, Carpenter, WT (2018). Preventive strategies for mental health. Lancet Psychiatry 5, 591–604.
Baldwin, P, Browne, D, Scully, PJ, Quinn, JF, Morgan, MG, Kinsella, A, Owens, JM, Russell, V, O’Callaghan, E, Waddington, JL (2005). Epidemiology of first-episode psychosis: illustrating the challenges across diagnostic boundaries through the Cavan/Monaghan study at 8 years. Schizophrenia Bulletin 31, 624–638.
Barch, DM, Bustillo, J, Gaebel, W, Gur, R, Heckers, S, Malaspina, D, Owen, MJ, Schultz, S, Tandon, R, Tsuang, M, van Os, J, Carpenter, W (2013). Logic and justification for dimensional assessment of symptoms and related phenomena in psychosis: relevance to DSM-5. Schizophrenia Research 150, 31–35.
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium
(2018). Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes. Cell 173, 1705–1715.
Birnbaum, R, Weinberger, DR (2017). Genetic insights into the neurodevelopmental origins of schizophrenia. Nature Reviews Neuroscience 18, 727–740.
Birur, B, Kraguljac, NV, Shelton, RC, Lahti, AC (2017). Brain structure, function, and neurochemistry in schizophrenia and bipolar disorder—a systematic review of the magnetic resonance neuroimaging literature. NPJ Schizophrenia 3, 15 doi: 10.1038/s41537-017-0013-9.
Bortolato, B, Kohler, CA, Evangelou, E, Leon-Caballero, J, Solmi, M, Stubbs, B, Belbasis, L, Pacchiarotti, I, Kessing, LV, Berk, M, Vieta, E, Carvalho, AF (2017). Systematic assessment of environmental risk factors for bipolar disorder: an umbrella review of systematic reviews and meta-analyses. Bipolar Disorders 19, 84–96.
(2018). Analysis of shared heritability in common disorders of the brain. Science 360, pii: eaap8757. doi: 10.1126/science.aap8757.
Brown, AS (2011). The environment and susceptibility to schizophrenia. Progress in Neurobiology 93, 23–58.
Browne, S, Clarke, M, Gervin, M, Waddington, JL, Larkin, C, O’Callaghan, E (2000). Determinants of quality of life at first presentation with schizophrenia. British Journal of Psychiatry 176, 173–176.
Cardno, AG, Owen, MJ (2014). Genetic relationship between schizophrenia, bipolar disorder, and schizoaffective disorder. Schizophrenia Bulletin 40, 504–515.
Carpenter, WT (2018). Clinical high risk controversies and challenges for the experts. Schizophrenia Bulletin 44, 223–225.
Castillejos, MC, Martin-Perez, C, Moreno-Kustner, B (2018). A systematic review and meta-analysis of the incidence of psychotic disorders: the distribution of rates and the influence of gender, urbanicity, immigration and socio-economic level. Psychological Medicine 48, 2101–2115. doi: 10.1017/S0033291718000235.
Clarke, M, McDonough, CM, Doyle, R, Waddington, JL (2016). Are we really impacting duration of untreated psychosis and does it matter? Longitudinal perspectives on early intervention from the Irish public health services. Psychiatric Clinics of North America 39, 175–186.
Correll, CU, Galling, B, Pawar, A, Krivko, A, Bonetto, C, Ruggeri, M, et al. (2018). Comparison of early intervention services vs treatment as usual for early-phase psychosis: A systematic review, meta-analysis and meta-regression. JAMA Psychiatry 75, 555–565.
Craddock, N, Owen, MJ (2010). The Kraepelinian dichotomy – going, going… but still not gone. British Journal of Psychiatry 196, 92–95.
Craddock, N, Sklar, P (2013). Genetics of bipolar disorder. Lancet 381, 1654–1662.
Cross-Disorder Group of the Psychiatric Genomics Consortium
(2013a). Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 381, 1371–1379.
Cross-Disorder Group of the Psychiatric Genomics Consortium
(2013b). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics 45, 984–994.
Davies, C, Cipriani, A, Ioannidis, JPA, Radua, J, Stahl, D, Provenzani, U, McGuire, P, Fusar-Poli, P (2018). Lack of evidence to favor specific preventive interventions in psychosis: a network meta-analysis. World Psychiatry 17, 196–209.
Davis, J, Eyre, H, Jacka, FN, Dodd, S, Dean, O, McEwen, S, Debnath, M, McGrath, J, Maes, M, Amminger, P, McGorry, PD, Pantelis, C, Berk, M (2016). A review of vulnerability and risks for schizophrenia: beyond the two hit hypothesis. Neuroscience & Biobehavioral Reviews 65, 185–194.
Demjaha, A, MacCabe, JH, Murray, RM (2012). How genes and environmental factors determine the different neurodevelopmental trajectories of schizophrenia and bipolar disorder. Schizophrenia Bulletin 38, 209–214.
Domschke, K (2013). Clinical and molecular genetics of psychotic depression. Schizophrenia Bulletin 39, 766–775.
European Network of National Networks Studying Gene-Environment Interactions in Schizophrenia
(2014). Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations. Schizophrenia Bulletin 40, 729–736.
Fusar-Poli, P, Borgwardt, S, Bechdolf, A, Addington, J, Riecher-Rössler, A, Schultze-Lutter, F, et al. (2013). The psychosis high-risk state: a comprehensive state-of-the-art review. JAMA Psychiatry 70, 107–120.
Fusar-Poli, P, Cappucciati, M, Rutigliano, G, Heslin, M, Stahl, D, Brittenden, Z, Caverzasi, E, McGuire, P, Carpenter, WT (2016). Diagnostic stability of ICD/DSM first episode psychosis diagnoses: meta-analysis. Schizophrenia Bulletin 42, 1395–1406.
Hennessy, RJ, Baldwin, PA, Browne, DJ, Kinsella, A, Waddington, JL (2007). Three-dimensional laser surface imaging and geometric morphometrics resolve frontonasal dysmorphology in schizophrenia. Biological Psychiatry 61, 1187–1194.
Hennessy, RJ, Baldwin, PA, Browne, DJ, Kinsella, A, Waddington, JL (2010). Frontonasal dysmorphology in bipolar disorder by 3D laser surface imaging and geometric morphometrics: comparisons with schizophrenia. Schizophrenia Research 122, 63–71.
Hilker, R, Helenius, D, Fagerlund, B, Skytthe, A, Christensen, K, Werge, TM, Nordentoft, M, Glenthoj, B (2017). Heritability of schizophrenia and schizophrenia spectrum based on the nationwide Danish twin register. Biological Psychiatry 83, 492–498.
Howes, OD, McCutcheon, R, Owen, MJ, Murray, RM (2017). The role of genes, stress, and dopamine in the development of schizophrenia. Biological Psychiatry 81, 9–20.
Howes, OD, Murray, RM (2014). Schizophrenia: an integrated sociodevelopmental-cognitive model. Lancet 383, 1677–1687.
Kahn, RS, Sommer, IE, Murray, RM, Meyer-Lindenberg, A, Weinberger, DR, Cannon, TD, O’Donovan, M, Correll, CU, Kane, JM, van Os, J, Insel, TR (2015). Schizophrenia. Nature Reviews Disease Primers 1, 15067. doi: 10.1038/nrdp.2015.67.
Kelly, BD, O’Callaghan, E, Waddington, JL, Feeney, L, Browne, S, Scully, PJ, Clarke, M, Quinn, JF, McTigue, O, Morgan, MG, Kinsella, A, Larkin, C (2010). Schizophrenia and the city: a review of literature and prospective study of psychosis and urbanicity in Ireland. Schizophrenia Research 116, 75–89.
Keshavan, MS, Schooler, NR (1992). First-episode studies in schizophrenia: criteria and characterization. Schizophrenia Bulletin 18, 491–513.
Kingston, T, Scully, PJ, Browne, D, Baldwin, PA, Kinsella, A, O’Callaghan, E, Waddington, JL (2018). Functional outcome and service engagement inn major depressive disorder with psychotic features: comparisons with schizophrenia, schizoaffective disorder and bipolar disorder in a 6-year follow-up of the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS). CNS Neuroscience & Therapeutics 24, 633–640.
Kingston, T, Scully, PJ, Browne, D, Baldwin, P, Kinsella, A, Russell, V, O’Callaghan, E, Waddington, JL (2013). Diagnostic trajectory, interplay and convergence/divergence across all 12 DSM-IV psychotic diagnoses: 6-year follow-up of the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS). Psychological Medicine 43, 2523–2533.
Kirch, DG, Lieberman, JA, Matthews, SM (1992). First-episode psychosis. Schizophrenia Bulletin 18, 177–178.
Kirkbride, JB, Errazuriz, A, Croudace, TJ, Morgan, C, Jackson, D, Boydell, J, Murray, RM, Jones, PB (2012). Incidence of schizophrenia and other psychoses in England, 1950-2009: a systematic review and meta-analyses. PLOS One 7, e31660. doi: 10.1371/journal.pone.0031660.
Lally, J, Ajnakina, O, Stubbs, B, Cullinane, M, Murphy, KC, Gaughran, F, Murray, RM (2017). Remission and recovery from first-episode psychosis in adults: systematic review and meta-analysis of long-term outcome studies. British Journal of Psychiatry 211, 350–358.
Marcucio, R, Hallgrimsson, B, Young, NM (2015). Facial morphogenesis: physical and molecular interactions between the brain and face. Current Topics in Developmental Biology 115, 299–320.
Marcucio, RS, Young, NM, Hu, D, Hallgrimsson, B (2011). Mechanisms that underlie co-variation of the brain and face. Genesis 49, 177–189.
McCauley, M, Rooney, S, Clarke, C, Carey, T, Owens, J (2003). Home-based treatment in Monaghan: the first two years. Irish Journal of Psychological Medicine 20, 11–14.
McGorry, PD, Hartmann, JA, Spooner, R, Nelson, B (2018). Beyond the “at risk mental state” concept: transitioning to transdiagnostic psychiatry. World Psychiatry 17, 133–142.
McGrath, JJ (2005). Myths and truths about schizophrenia epidemiology. Acta Psychiatrica Scandinavica 111, 4–11.
Millan, MJ, Andrieux, A, Bartzokis, G, Cadenhead, K, Dazzan, P, Fusar-Poli, P, et al. (2016). Altering the course of schizophrenia: progress and perspectives. Nature Reviews Drug Discovery 15, 485–515.
Million, T, Grossman, S, Meagher, S (2004). Masters of the Mind: Exploring the Story of Mental Illness from Ancient Times to the New Millennium. John Wiley: Hoboken, NJ.
Murray, RM, Bhavsar, V, Tripoli, G, Howes, O (2017). 30 years on: How the neurodevelopmental hypothesis of schizophrenia morphed into the developmental risk factor model of psychosis. Schizophrenia Bulletin 43, 1190–1196.
Nwachukwu, I, Nkire, N, Russell, V (2014). Profile and activities of a rural home-based treatment service in Ireland. International Journal of Psychiatry in Clinical Practice 18, 125–130.
Nkire, N, Sardinha, S, Nwosu, B, McDonough, CM, De Coteau, PA, Duffy, I, Waddington, JL, Russell, V (2015). Evaluation of knowledge and attitudes among primary care physicians in Cavan-Monaghan as ‘gatekeepers-in-waiting’ for the introduction of Carepath for Overcoming Psychosis Early (COPE). Early Intervention in Psychiatry 9, 141–150.
O’Donoghue, B, Roche, E, Lane, A (2016). Neighbourhood level social deprivation and the risk of psychotic disorders: a systematic review. Social Psychiatry and Psychiatric Epidemiology 51, 941–950.
Oliver, D, Davies, C, Crossland, G, Lim, S, Gifford, G, McGuire, P, Fusar-Poli, P (2018). Can we reduce the duration of untreated psychosis? A systematic review and meta-analysis of controlled intervention studies. Schizophrenia Bulletin 44, 1362–1372. doi: 10.1093/schbul/sbx166.
Omer, S, Finnegan, M, Pringle, DG, Kinsella, A, Fearon, P, Russell, V, O’Callaghan, E, Waddington, JL (2016). Socioeconomic status at birth and risk for first episode psychosis in rural Ireland: eliminating the features of urbanicity in the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS). Schizophrenia Research 173, 84–89.
Omer, S, Kirkbride, JB, Pringle, DG, Russell, V, O’Callaghan, E, Waddington, JL (2014). Neighbourhood-level socio-environmental factors and incidence of first episode psychosis by place at onset in rural Ireland: the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS). Schizophrenia Research 152, 152–157.
Owen, MJ (2014). New approaches to psychiatric diagnostic classification. Neuron 84, 564–571.
Owen, MJ, Sawa, A, Mortensen, PB (2016). Schizophrenia. Lancet 388, 86–97.
Owoeye, O, Kingston, T, Scully, PJ, Baldwin, P, Browne, D, Kinsella, A, Russell, V, O’Callaghan, E, Waddington, JL (2013). Epidemiological and clinical characterization following a first psychotic episode in major depressive disorder: comparisons with schizophrenia and bipolar I disorder in the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS). Schizophrenia Bulletin 39, 756–765.
Parellada, M, Gomez-Vallejo, S, Burdeus, M, Arango, C (2017). Developmental differences between schizophrenia and bipolar disorder. Schizophrenia Bulletin 43, 1176–1189.
Pearlson, GD (2015). Etiologic, phenomenologic, and endophenotypic overlap of schizophrenia and bipolar disorder. Annual Review of Clinical Psychology 11, 251–281.
Radua, J, Ramella-Cravaro, V, Ioannidis, JPA, Reichenberg, A, Phiphopthatsanee, N, Amir, T, Yenn Thoo, H, Oliver, D, Davies, C, Morgan, C, McGuire, P, Murray, RM, Fusar-Poli, P (2018) What causes schizophrenia? An umbrella review of risk and protective factors. World Psychiatry 17, 49–66.
Ram, R, Bromet, EJ, Eaton, WW, Pato, C, Schwartz, JE (1992). The natural course of schizophrenia: a review of first admission studies. Schizophrenia Bulletin 18, 185–207.
Renwick, L, Gavin, B, McGlade, N, Lacey, P, Goggins, R, Jackson, D, Turner, N, Foley, S, McWilliams, S, Behan, C, Lawlor, E, Cullen, W, O’Callaghan, E (2008). Early intervention service for psychosis: views from primary care. Early Intervention in Psychiatry 2, 285–290.
Russell, V, Nkire, N, Kingston, T, Waddington, JL (2019). Forging successful partnerships in psychosis research: lessons from the Cavan-Monaghan First Episode Psychosis Study (CAMFEPS). Irish Journal of Psychological Medicine (in press).
Santesteban-Echarri, O, Paino, M, Rice, S, Gonzalez-Blanch, C, McGorry, P, Gleeson, J, Alvarez-Jimenez, M (2017). Predictors of functional recovery in first-episode psychosis: a systematic review and meta-analysis of longitudinal studies. Clinical Psychology Reviews 58, 59–75.
Schizophrenia Working Group of the Psychiatric Genomics Consortium
(2014) Biological insights from 108 schizophrenia-associated genetic loci. Nature 511, 421–427.
Sullivan, PF, Agrawal, A, Bulik, CM, Andreassen, OA, Borglum, AD, Breen, G, Cichon, S, Edenberg, HJ, Faraone, SV, Gelernter, J, Mathews, CA, Nievergelt, CM, Smoller, JW, O’Donovan, MC, Psychiatric Genomics Consortium (2018). Psychiatric genomics: an update and agenda. American Journal of Psychiatry 175, 15–27.
Tost, H, Meyer-Lindenberg, A (2012). Puzzling over schizophrenia: schizophrenia, social environment and the brain. Nature Medicine 18, 211–213.
Van der Werf, M, Hanssen, M, Kohler, S, Verkaaik, M, Verhey, FR, RISE Investigators, van Winkel, R, van Os, J, Allardyce, J (2014). Systematic review and collaborative recalculation of 133693 incident cases of schizophrenia. Psychological Medicine 44, 9–16.
van Os, J, Kapur, S (2009). Schizophrenia. Lancet 374, 635–645.
van Os, J, Reininghaus, U (2016). Psychosis as a transdiagnostic and extended phenotype in the general population. World Psychiatry 15, 118–124.
Vieta, E, Berk, M, Scxhulze, TG, Carvalho, AF, Suppes, T, Calabrese, JR, Gao, K, Miskowiak, KW, Grande, I (2018). Bipolar disorders. Nature Reviews Disease Primers 4, 18008. doi: 10.1038/nrdp.2018.8.
Waddington, JL, Brown, AS, Schaefer, CA, Goetz, RR, Bresnahan, M, Susser, ES (2008). Congenital anomalies and early functional impairments in a prospective birth cohort: risk of schizophrenia-spectrum disorder in adulthood. British Journal of Psychiatry 192, 264–267.
Waddington, JL, Buckley, PF (2013). Psychotic depression: an underappreciated window to explore the dimensionality and pathobiology of psychosis. Schizophrenia Bulletin 39, 754–755.
Waddington, JL, Hennessy, RJ, O’Tuathaigh, CMP, Owoeye, O, Russell, V (2012). Schizophrenia and the lifetime trajectory of psychotic illness: developmental neuroscience and pathobiology. In The Origins of Schizophrenia (ed. Brown, A. S. and Harrison, P. H.), pp. 3–21. Columbia University Press: New York.
Waddington, JL, Larkin, C (1993). A new developmental epidemiology of schizophrenia: the HRB Schizophrenia Research Unit, 1991-92, and contemporary perspectives of the disease. Irish Journal of Psychological Medicine 10, 56–59.
Waddington, JL, Kingston, T, Nkire, N, Russell, V (2019). Major depressive disorder with psychotic features: confronting and resolving the dimensional challenge. In Psychotic Disorders: Comprehensive Conceptualization and Treatments (ed. van Os, J., Tamminga, C. A., Ivleva, E. I. and Reininghaus, U.). Oxford University Press: Oxford. (in press)
Weinberger, DR (2017). Future of days past: neurodevelopment and schizophrenia. Schizophrenia Bulletin 43, 1164–1168.
Xu, T, Chan, RCK, Compton, MT (2011). Minor physical anomalies in patients with schizophrenia, unaffected first-degree relatives, and healthy controls: a meta-analysis. PLoS ONE 6, e24129.
Zhen, XC, Waddington, JL (2018). Emerging and evolving concepts in the pathobiology and treatment of psychosis. CNS Neuroscience & Therapeutics 24, 583–585.