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Using sedatives–hypnotics or opioids in older adults: a narrow path

  • Simon J. C. Davies (a1) (a2) and Benoit H. Mulsant (a1) (a2)

Extract

This issue of International Psychogeriatrics contains three papers from three continents that explore the use of sedatives–hypnotics and opioids in the treatment of older adults (Hamina et al., 2018; Machado-Duque et al., 2018; Tseng et al., 2018), and a fourth paper reporting on a qualitative study that addresses the broader question of training needs in dementia in a setting of rapid economic and demographic changes (Xu et al., 2018).

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References

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Baldwin, D. S. et al. (2013). Benzodiazepines: risks and benefits. A reconsideration. Journal of Psychopharmacology, 27, 967971.
Chibnall, J. T., Tait, R. C. and Harman, B. (2005). Effect of acetaminophen on behavior, well-being, and psychotropic medication use in nursing home residents with moderate-to-severe dementia. Journal of the American Geriatrics Society, 53, 19211929.
Crowe, S. F. and Stranks, E. K. (2017). The residual medium and long-term cognitive effects of benzodiazepine use: an updated meta-analysis. Archives of Clinical Neuropsychology. Epublished ahead of print, doi:10.1093/arclin/acx120.
Davies, S. J. et al. (2018). Sequential drug treatment algorithm for agitation and aggression in Alzheimer's and mixed dementia. Journal of Psychopharmacology, 32, 509523.
FDA Drug Safety Communication (2016). FDA Warns About Serious Risks and Death When Combining Opioid Pain or Cough Medicines with Benzodiazepines; Requires Its Strongest Warning. Available at: https://www.fda.gov/Drugs/DrugSafety/ucm518473.htm; accessed on April 30, 2018.
Gray, S. L. et al. (2016) Benzodiazepine use and risk of incident dementia or cognitive decline: prospective population based study. BMJ, 352, i90.
Hamina, A. et al. (2018). Impact of opioid initiation on antipsychotic and benzodiazepine and related drug use among persons with Alzheimer's disease. International Psychogeriatrics, 30, 947956.
He, W., Goodkind, D. and Kowal, P. (2016). An Aging World: 2015, International Population Reports, P95/16-1. Washington, DC: U.S. Government Publishing Office.
Machado-Duque, M. E., Castaño-Montoya, J. P., Medina-Morales, D. A., Castro-Rodríguez, A., González-Montoya, A. and Machado-Alba, J. E. (2018). Association between the use of benzodiazepines and opioidswith the risk of falls and hip fractures in older adults. International Psychogeriatrics, 30, 941946.
Tseng, H. Y. et al. (2018). Sedative-hypnotic drug use among community-dwelling elderly in Taiwan. International Psychogeriatrics, 30, 957965.
Xu, L., Hsiao, H. Y., Denq, W. and Chi, I. (2018). Training needs for dementia care in China from theperspectives of mental health providers: who, what, and how. International Psychogeriatrics, 30, 929940.

Using sedatives–hypnotics or opioids in older adults: a narrow path

  • Simon J. C. Davies (a1) (a2) and Benoit H. Mulsant (a1) (a2)

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