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Depression risk in patients with heart failure in primary care practices in Germany

Published online by Cambridge University Press:  16 June 2016

Marcel Konrad ,
Jens Bohlken ,
Michael A Rapp  and
Karel Kostev
Marcel Konrad
Affiliation:
Fresenius University of Applied Sciences, Idstein, Germany
Jens Bohlken
Affiliation:
Psychiatric Practice Bohlken, Berlin, Germany
Michael A Rapp
Affiliation:
Department of Social and Preventive Medicine, University of Potsdam, Potsdam, Germany
Karel Kostev*
Affiliation:
IMS Health, Frankfurt am Main, Germany
*
Correspondence should be addressed to: Prof. Dr Karel Kostev, IMS Health, Epidemiology, Darmstädter Landstraße 1089, 60598 Frankfurt am Main, Germany. Phone: +49 69 6604 4878. Email: kkostev@de.imshealth.com.
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Abstract

Background:

The goal of this study was to estimate the prevalence of and risk factors for diagnosed depression in heart failure (HF) patients in German primary care practices.

Methods:

This study was a retrospective database analysis in Germany utilizing the Disease Analyzer® Database (IMS Health, Germany). The study population included 132,994 patients between 40 and 90 years of age from 1,072 primary care practices. The observation period was between 2004 and 2013. Follow-up lasted up to five years and ended in April 2015. A total of 66,497 HF patients were selected after applying exclusion criteria. The same number of 66,497 controls were chosen and were matched (1:1) to HF patients on the basis of age, sex, health insurance, depression diagnosis in the past, and follow-up duration after index date.

Results:

HF was a strong risk factor for diagnosed depression (p < 0.0001). A total of 10.5% of HF patients and 6.3% of matched controls developed depression after one year of follow-up (p < 0.001). Depression was documented in 28.9% of the HF group and 18.2% of the control group after the five-year follow-up (p < 0.001). Cancer, dementia, osteoporosis, stroke, and osteoarthritis were associated with a higher risk of developing depression. Male gender and private health insurance were associated with lower risk of depression.

Conclusions:

The risk of diagnosed depression is significantly increased in patients with HF compared to patients without HF in primary care practices in Germany.

Keywords

depressionprimary carerisk factorsantidepressants
Type
Research Article
Information
International Psychogeriatrics , Volume 28 , Issue 11 , November 2016 , pp. 1889 - 1894
Copyright
Copyright © International Psychogeriatric Association 2016 

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