Skip to main content Accessibility help
×
Home

Circadian Rhythm-Related Behavioral Disturbances and Structural Hypothalamic Changes in Alzheimer's Disease

  • Witte J. G. Hoogendijk (a1) (a2), Eus J. W. van Someren (a1), Majid Mirmiran (a1), Michel A. Hofman (a1), Paul J. Lucassen (a1), Jiang-Ning Zhou (a1) and Dick F. Swaab (a1)...

Extract

Age-related changes in circadian rhythm (e.g., fragmented sleep-wake patterns) occur in many older persons but are particularly pronounced in patients with Alzheimer's disease. In these patients, disruptions of circadian rhythms can be severe enough to increase mental decline, agitation during the day, and restlessness at night. Moreover, patients whose nocturnal restlessness disrupts the sleep of the caregiver are more likely to be institutionalized than those who have cognitive impairment alone.

Copyright

Circadian Rhythm-Related Behavioral Disturbances and Structural Hypothalamic Changes in Alzheimer's Disease

  • Witte J. G. Hoogendijk (a1) (a2), Eus J. W. van Someren (a1), Majid Mirmiran (a1), Michel A. Hofman (a1), Paul J. Lucassen (a1), Jiang-Ning Zhou (a1) and Dick F. Swaab (a1)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed