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Report on the satellite meeting on malaria

Published online by Cambridge University Press:  19 September 2011

R. E. Sinden
Affiliation:
Department of Pure & Applied Biology, Imperial College, London SW7 2AZ, England
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Extract

Eight papers were presented on topics ranging from the dissemination of drug resistance in Africa; the application of new antimalarial compounds; the basic biology of the malarial parasite; and methods for in vitro culture and its analysis, to the interaction of the malarial parasite with the infected host with particular reference to host genetic factors responsible for parasite survival.

Type
Research Article
Copyright
Copyright © ICIPE 1986

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References

REFERENCES

Ballou, M. R., Rothbard, J., Wirtz, R. A., Gordon, D. M., Willims, J. S., Gore, R. W., Schneider, I., Hollingdale, M. R., Beaudoin, R. L., Maloy, W. L., Miller, L. H. and Hockmeyer, W. T. (1985) Immunogenicity of synthetic peptides from circumsporozoite protein of Plasmodium falciparum. Science 228, 996999.Google Scholar
Brockleman, C. R., Tan-ariya, P. and Laovanitch, R. (1985) Observation in complete schizogony of Plasmodium vivax in vitro. J. Protozool. 32, 7680.Google Scholar
Carter, R. and Miller, L. H. (1979) Evidence of environmental modulation of gametocytogenesis in Plasmodium falciparum in continuous culture. Bull. Wld tilth Org. 57, 3752.Google ScholarPubMed
Hammond, D. J., Burchell, J. R. and Pudney, M. (1985) Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2–(4-t−butylcyclohexyl)-3-hydroxy- 1, 4-naphthoquinone in vitro. Molec. Biochem. Parasit. 14, 97109.CrossRefGoogle Scholar
Hogerseil, H. V., Hogewoning, H. A., Doom, J. W. van, Wernsdorfer, W. H. and Van der Kaay, H. J. (1986) In vitro assessment of sensitivity of Plasmodium falciparum to chloroquine and mefloquine in Ghana. Trans. R. Soc. trop. Med. Hyg. 179, In press.Google Scholar
Inselberg, J. (1985) Induction and isolation of artimesinineresistant mutants in Plasmodium falciparum. Am. J. trop. Med. Hyg. 24, 417418.CrossRefGoogle Scholar
Janse, C. J., Mons, B., Croon, J. J. A. B. and Van der Kaay, H. J. (1984) Long-term in vitro cultures of Plasmodium berghei and preliminary observations on gametocytogenesis. Int. J. Parasit. 14, 317320.Google Scholar
Janse, C. J., Van der Klooster, P. F. J., Van der Kaay, H. J., Van der Ploeg, M. and Overdulve, P. (1986) Rapid repeated DNA replication during microgametogenesis and DNA synthesis in young zygotes of Plasmodium berghei. Trans. R. Soc. trop. Med. Hyg. 79, In press.Google Scholar
Kilejian, A. (1978) Histidine-rich protein as a model malaria vaccine. Science 201, 922924.Google Scholar
Killick-Kendrick, R. and Warren, M. (1968) Primary exoerythrocytic schizonts of a mammalian Plasmodium as a source of gametocytes. Nature 220, 191192.Google Scholar
Livingstone, F. B. (1971) Malaria and human polymorphisms. A. Rev. Genet. 5, 3365.CrossRefGoogle Scholar
Luzzatto, L. (1979) Genetics of red cells and susceptibility to malaria. J. Am. Soc. Haemat. 54, 961976.Google ScholarPubMed
Meis, J. F. G. M., Jap, P. H. K., Verhave, J. P. and Meuwissen, J. H. E. T. (1983a) Ultrastructural studies of a vesicle system associated endoplasmic reticulum in exoerythrocytic forms of Plasmodium berghei. J. Protozool. 30, 111114.Google Scholar
Meis, J. F. G. M., Verhave, J. P., Jap, P. H. K. and Meuwissen, J. H. E. T. (1983b) An ultrastructural study on the role of the Kupffer cells in the process of infection by Plasmodium berghei sporozoites in rats. Parasitology 86, 231242.CrossRefGoogle Scholar
Meis, J. F. G. M., Verhave, J. P., Wirtz, P. and Meuwissen, J. H. E. T. (1984) Histochemical observations on the exoerythrocytic malaria parasite Plasmodium berghei in rat liver. Histochemistry 81, 417425.CrossRefGoogle ScholarPubMed
Meis, J. F. G. M., Verhave, J. P., Brouwer, A. and Meuwissen, J. H. E. T. (1985a) Electron microscopic studies on the interaction of rat Kupffer cells and Plasmodium berghei sporozoites. Z. Parasit. 71, 473483.CrossRefGoogle ScholarPubMed
Meis, J. F. G. M., Verhave, J. P., Jap, P. H. K. and Meuwissen, J. H. E. T. (1985b) Transformation of sporozoites of Plasmodium berghei into exoerythrocytic forms in the liver of its mammalian host. Cell Tiss. Res. 241, 353360.Google Scholar
Mons, B., Janse, C. J., Croon, J. A. B. and Van der Kaay, H. J. (1983) In vitro culture of Plasmodium berghei using a new suspension system. Int. J. Parasit. 13, 213217.Google Scholar
Mons, B., Janse, C. J., Boorsma, E. G. and Van der Kaay, H. J. (1986) Synchronised erythrocytic schizogony and gametocytogenesis of Plasmodium berghei in vivo and in vitro. Parasitology. In press.CrossRefGoogle Scholar
Sinden, R. E. (1983) The cell biology of sexual development in Plasmodium. Parasilology 86, 728.Google Scholar
Sinden, R. E. (1986) Gametocytogenesis in Plasmodium spp. and observations on the meiotic division. Annls Soc. belg. Med. trop. 65, In press.Google Scholar
Sinden, R. E. and Hartley, R. (1986) Identification of the meiotic division in malarial parasites. J. Protozool. In press.Google Scholar
Usanga, E. A. and Luzzatto, L. (1985) Adaptation of Plasmodium falciparum to glucose-6-phosphate dehydrogenase-deficient host red cells by production of parasite encoded enzyme. Nature 313, 793795.Google Scholar
Van der Kaay, H. J., Overbosch, D., Stuiver, P. C. and Wismans, P. J. (1984) Malaria chemoprophylaxis for multiple drug resistant Plasmodium falciparum in Africa: an increasing problem. Trop. geogr. Med. 36, 317322.Google ScholarPubMed
Van der Kaay, H. J., Wernsdorfer, W. H. and Froeling, F. M. J. A. (1986) In vitro response of Plasmodium falciparum to mefloquine: studies conducted in West and East Africa. Annls Soc. beige. Med. trop. 65, In press.Google Scholar
Verhave, J. P. and Meis, J. F. G. M. (1984) The biology of tissue forms and other asexual stages in mammalian plasmodia. Experientia 40, 13171329.CrossRefGoogle ScholarPubMed
Wallach, M. (1982) Efficient extraction and translation of Plasmodium falciparum messenger RNA. Molec. Biochem. Parasit. 6, 335342.Google Scholar
Young, J. F., Hockmeyer, W. T., Gross, M., Ballou, W. R., Wirtz, R. A., Trosper, J. H., Beaudoin, R. L., Hollingdale, M. R., Miller, L. H., Diggs, C. L. and Rosenberg, M. (1985) Expression of Plasmodium falciparum circumsporozoite proteins in Escherchia coli for potential use in a human malaria vaccine. Science 228, 958962.CrossRefGoogle Scholar
Zavala, F., Tam, J. P., Hollingdale, M. R., Cochrane, A. H., Quakyi, I., Nussenzweig, R. S. and Nussenzweig, V. (1985) Rationale for development of a synthetic vaccine against Plasmodium falciparum malaria. Science 228, 14361440.CrossRefGoogle ScholarPubMed