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Effect of plant quinones on insect flight muscle mitochondria

Published online by Cambridge University Press:  19 September 2011

E. N. Magiri ,
V. N. Konji ,
D. W. Makawiti  and
J. Midiwo
E. N. Magiri
Affiliation:
Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
V. N. Konji
Affiliation:
Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
D. W. Makawiti
Affiliation:
Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
J. Midiwo
Affiliation:
Department of Chemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
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Abstract

The effect of four biologically active and naturally occurring plant quinones, namely maesanin, maesaquinone, embelin and juglone on the respiration of mitochondria isolated from Glossina morsitans morsitans, Schistoscerca gregaria and Periplaneta americana was investigated. The rate of oxygen consumption by the mitochondria was measured using an oxygen electrode. Maesanin inhibited the mitochondrial electron transport chain at a level before cytochrome C whereas maesaquinone and embelin uncoupled the mitochondria. Juglone inhibited respiration in G. m. morsitans mitochondria and uncoupled those of S. gregaria and P. americana.

Résumé

L'effet de 4 quinones vegetales et actives biologiquements, notament maesanine, maesaquinone, embeline et juglone, a été étudié sur les mitochondries respiratoires isolées de Glossina morsitans morsitans, Schistocerca gregaria et Periplaneta americana. Le taux de consommation d'oxygène par les mitochondries a été mesurée à l'aide d'un electrode à oxygène. La maesanine a inhibé la chaine de transport de l'électron des mitochondries à un stade avant le cytochrome C tandis que le maesaquinone et l'embeline ont fait détacher la membrane mitochondriale. Le juglone a inhibé la respiration chez les mitochondries de G. m. morsitans et fait détacher celles de S. gregaria et P. americana.

Keywords

plant quinonesinsect flight muscle mitochondriarespirationquinones végétalesmitochondries des muscles de vol de l'insecterespiration
Type
Research Articles
Information
International Journal of Tropical Insect Science , Volume 16 , Issue 2 , June 1995 , pp. 183 - 189
Copyright
Copyright © ICIPE 1995

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