The high stellar densities at the centre of some globular clusters provide prolific breeding grounds for exotic stars, e.g., the 11 msec pulsars in 47 Tuc and numerous blue stragglers. The same high density of stars as viewed on the sky makes ground-based photometry problematic for variable star detection. Even a very few tight binaries can be of fundamental importance for the dynamic evolution of the cluster core. We present results of a continuous 40-hour sequence of U-band CCD exposures acquired with WF/PC on HST. The high spatial resolution coupled with a stable PSF allows nearly Poisson limited time series on some 20,000 stars. The 1000 second sampling and long coverage provide excellent sensitivity to W UMa and δ Scuti variations. Light curves are shown for selected variables and the relative frequencies of binary and variable stars are discussed.