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What Is the Source of Bloodstream Infection due to Vancomycin-Resistant Enterococci in Persons with Mucosal Barrier Injury?

  • Mini Kamboj (a1) (a2), Rachel Blair (a1), Natalie Bell (a1), Janet Sun (a1) (a2), Janet Eagan (a1) and Kent Sepkowitz (a1) (a2)...
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Abstract

Copyright

Corresponding author

Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (kambojm@mskcc.org)

References

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1. Horan, TC, Andrus, M, Dudeck, MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36(5):309332, doi:10.1016/j.ajic.2008.03.002.
2. Fraser, TG, Gordon, SM. CLABSI rates in immunocompromised patients: a valuable patient centered outcome? Clin Infect Dis 2011;52(12):14461450, doi:10.1093/cid/cir200.
3. Raad, I, Hanna, HA, Alakech, B, Chatzinikolaou, I, Johnson, MM, Tarrand, J. Differential time to positivity: a useful method for diagnosing catheter-related bloodstream infections. Ann Intern Med 2004;140(1):1825.
4. Steinberg, JP, Robichaux, C, Tejedor, SC, Reyes, MD, Jacob, JT. Distribution of pathogens in central line-associated bloodstream infections among patients with and without neutropenia following chemotherapy: evidence for a proposed modification to the current surveillance definition. Infect Control Hosp Epidemiol 2013;34(2):171175, doi:10.1086/669082.
5. Ubeda, C, Taur, Y, Jenq, RR, et al. Vancomycin-resistant Entero-coccus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans. J Clin Investig 2010;120(12):43324341, doi:10.1172/jci43918.
6. Climo, MW, Sepkowitz, KA, Zuccotti, G, et al. The effect of daily bathing with Chlorhexidine on the acquisition of methicillinresistant Staphylococcus aureus, vancomycin-resistant Enterococ-cus, and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial. Crii Care Med 2009;37(6):18581865, doi:10.1097/CCM.ObO13e31819ffe6d.
7. See, I, Iwamoto, M, Allen-Bridson, K, Horan, T, Magill, SS, Thompson, ND. Mucosal barrier injury laboratory-confirmed bloodstream infection: results from a field test of a new national healthcare safety network definition. Infect Control Hosp Epidemiol 2013;34(8):769776, doi:10.1086/671281.
8. Homan, WL, Tribe, D, Poznanski, S, et al. Multilocus sequence typing scheme for Enterococcus faecium . J Clin Microbiol 2002;40(6):19631971.

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