Skip to main content Accessibility help

Vancomycin-Resistant Enterococcus (VRE) Transmission and Risk Factors in Contacts of VRE Carriers

  • Reham Kaki (a1) (a2), Yang Yu (a3), Cindy O’Neill (a4), Christine Lee (a1) (a3) (a4) (a5), Dominik Mertz (a1) (a4) (a6) and Hamilton Health Sciences Infection Prevention and Control Team...


During a 2-year period, the vancomycin-resistant enterococcus (VRE) acquisition rate was 10.9% (40/368) in patients who had shared a room with a newly detected VRE carrier. Exposure to vancomycin and to anti-anaerobic antibiotics were identified as independent risk factors for VRE acquisition. Sensitivity of the first rectal VRE screening was less than 50%.

Infect Control Hosp Epidemiol 2014;35(7):876–879


Corresponding author

Juravinski Hospital and Cancer Center, 711 Concession Street, Section M, Level 1, Room 3, Hamilton, Ontario L8V 1C3, Canada (


Hide All
1. DiazGranados, CA, Zimmer, SM, Klein, M, Jernigan, JA. Comparison of mortality associated with vancomycin-resistant and vancomycin-susceptible enterococcal bloodstream infections: a meta-analysis. Clin Infect Dis 2005;41(3):327333.
2. Siegel, JD, Rhinehart, E, Jackson, M, Chiarello, L. Management of multidrug-resistant organisms in health care settings, 2006. Am J Infect Control 2007;35(10 suppl 2):S165S193.
3. Tacconelli, E, Cataldo, MA. Vancomycin-resistant enterococci (VRE): transmission and control. Int J Antimicrob Agents 2008;31(2):99106.
4. Tacconelli, E, Karchmer, AW, Yokoe, D, D’Agata, EM. Preventing the influx of vancomycin-resistant enterococci into health care institutions, by use of a simple validated prediction rule. Clin Infect Dis 2004;39(7):964970.
5. Carmeli, Y, Eliopoulos, GM, Samore, MH. Antecedent treatment with different antibiotic agents as a risk factor for vancomycin-resistant Enterococcus. Emerg Infect Dis 2002;8(8):802807.
6. Bonten, MJ, Slaughter, S, Ambergen, AW, et al. The role of “colonization pressure” in the spread of vancomycin-resistant enterococci: an important infection control variable. Arch Intern Med 1998;158(10):11271132.
7. Drees, M, Snydman, DR, Schmid, CH, et al. Antibiotic exposure and room contamination among patients colonized with vancomycin-resistant enterococci. Infect Control Hosp Epidemiol 2008;29(8):709715.
8. Zhou, Q, Moore, C, Eden, S, Tong, A, McGeer, A. Factors associated with acquisition of vancomycin-resistant enterococci (VRE) in roommate contacts of patients colonized or infected with VRE in a tertiary care hospital. Infect Control Hosp Epidemiol 2008;29(5):398403.
9. Bass, P, Karki, S, Rhodes, D, et al. Impact of chlorhexidine-impregnated washcloths on reducing incidence of vancomycin-resistant enterococci colonization in hematology-oncology patients. Am J Infect Control 2013;41(4):345348.
10. Moore, C, Dhaliwal, J, Tong, A, et al. Risk factors for methicillin-resistant Staphylococcus aureus (MRSA) acquisition in roommate contacts of patients colonized or infected with MRSA in an acute-care hospital. Infect Control Hosp Epidemiol 2008;29(7):600606.


Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed