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Vancomycin Use During Left Ventricular Assist Device Support

Published online by Cambridge University Press:  02 January 2015

Rachel F. Eyler ,
Simona O. Butler ,
Paul C. Walker ,
Daryl D. DePestel ,
Martinus T. Spoor ,
Francis D. Pagani  and
Preeti N. Malani
Rachel F. Eyler
Affiliation:
Departments of Pharmacy Services, Ann Arbor, Michigan University of Michigan Health System and College of Pharmacy, Ann Arbor, Michigan
Simona O. Butler
Affiliation:
Departments of Pharmacy Services, Ann Arbor, Michigan
Paul C. Walker*
Affiliation:
Departments of Pharmacy Services, Ann Arbor, Michigan University of Michigan Health System and College of Pharmacy, Ann Arbor, Michigan
Daryl D. DePestel
Affiliation:
Departments of Pharmacy Services, Ann Arbor, Michigan University of Michigan Health System and College of Pharmacy, Ann Arbor, Michigan
Martinus T. Spoor
Affiliation:
Surgery, Section of Cardiothoracic Surgery, Ann Arbor, Michigan
Francis D. Pagani
Affiliation:
Surgery, Section of Cardiothoracic Surgery, Ann Arbor, Michigan
Preeti N. Malani
Affiliation:
Internal Medicine, Division of Infectious Diseases and Geriatric Medicine, Ann Arbor, Michigan Veterans Affairs Ann Arbor Healthcare System and Geriatric Research Education and Clinical Center, Ann Arbor, Michigan
*
University of Michigan Health System, Department of Pharmacy Services B2D301, Ann Arbor, MI 48109-0008) pcwalker@umich.edu)
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Abstract

We reviewed the frequency and duration of vancomycin use during 93 left ventricular assist device placements. Vancomycin prophylaxis was administered for a mean duration (± standard deviation) of 10.5 ± 11 days. Empirical vancomycin use was frequent, with a mean duration (± standard deviation) of therapy of 9.8 ± 9 days (median, 8 days) given during 81 (87%) of the implantations. The most common indications for empirical vancomycin treatment were isolated leukocytosis or driveline drainage. Strategies to improve vancomycin use during left ventricular assist device support should be considered.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 30 , Issue 5 , May 2009 , pp. 484 - 486
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2009

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