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The Use of a Combination Antibiogram to Assist with the Selection of Appropriate Antimicrobial Therapy for Carbapenemase-Producing Enterobacteriaceae Infections

  • Alice J. Hsu (a1), Karen C. Carroll (a2), Aaron M. Milstone (a3), Edina Avdic (a1), Sara E. Cosgrove (a4), Mercedes Vilasoa (a5) and Pranita D. Tamma (a3)...


Combination antibiograms can be used to evaluate organism cross-resistance among multiple antibiotics. As combination therapy is generally favored for the treatment of carbapenemase-producing Enterobacteriaceae (CPE), combination antibiograms provide valuable information about the combination of antibiotics that achieve the highest likelihood of adequate antibiotic coverage against CPE.

Infect. Control Hosp. Epidemiol. 2015;36(12):1458–1460


Corresponding author

Address correspondence to Pranita D. Tamma, MD, MHS, The Johns Hopkins University School of Medicine, Department of Pediatrics, Division of Infectious Diseases, 200 North Wolfe Street, Suite 3155, Baltimore, Maryland 21287 (


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