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A Typical Case of Cross-Acquisition? The Importance of Genotypic Characterization of Bacterial Strains

Published online by Cambridge University Press:  02 January 2015

Marc J.M. Bonten ,
Carlo A. Gaillard ,
Frank H. van Tiel ,
Siebe van der Geest  and
Ellen E. Stobberingh
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Abstract

A 33-year-old trauma patient died of Serratia marcescens pneumonia and septic shock. Isolates from this patient were phenotypically identical to strains isolated from the only other intensive care unit patient colonized with S marcescens. Although cross-acquisition was suspected strongly, serotyping and plasmid analysis demonstrated that the isolates were genotypically different, underscoring the importance of genotypic characterization.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 16 , Issue 7 , July 1995 , pp. 415 - 416
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1995

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References

1.Torres, A, Aznar, R, Gatell, JM, et al. Incidence, risk, and prognosis factors of nosocomial pneumonia in mechanically ventilated patients. Am Rev Respir Dis 1990:142:523–528.Google Scholar
2.Johanson, WG, Pierce, AK, Sanford, JPThomas, GD. Nosocomial respiratory infections with gram-negative bacilli: the significance of colonization of the respiratory tract. Am Intern Med 1972;77:701–706.Google Scholar
3.Heyland, D, Mandeli, LA. Gastric colonization by gram-negative bacilli and nosocomial pneumonia in the intensive care unit patient. Evidence for causation. Chest 1992;101:187–193.Google Scholar
4.Wenzel, RPThompson, RL. Landry, SM. et al. Hospital-acquired infections in intensive care unit patients: an overview with emphasis on epidemics. Infect Control 1983;4:371–375.Google Scholar
5.Doebbeling, BN, Stanley, GISheetz, CTet al. Comparative efficacy of alternative hand-washing agents in reducing nosocomial infections in intensive care units. N Engl J Med 1992;327:88–93.Google Scholar
6.Guinee, PAM, Jansen, WM. Maas, HMESerotyping of Serratia marcescens using passive hemagglutination. Zentral Bakterial und Hyg 1987;A264:105–119.Google Scholar
7.Sambrook, J, Fritsch, EEManiatis, TMolecular Cloning A Laboratory Manual. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory; 1989.Google Scholar
8.Bonten, MJM, Gaillard, CA, Johanson, WG, et al. Colonization in patients receiving and not-receiving topical antimicrobial prophylaxis. Am J Respir Crit Care Med 1994;150:1332–1340.Google Scholar