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Topics in Clinical Microbiology Flavobacterium Meningosepticum

Published online by Cambridge University Press:  02 January 2015

Hilda Ratner*
Affiliation:
Clinical Microbiology Laboratory, Vanderbilt University, Nashville, Tennessee

Extract

Flavobacterium meningosepticum, found as a saprophyte in water, soil and the hospital environment, has a relatively short history as a human pathogen. In 1944 Shulman and Johnson reported a case of meningitis in a premature infant due to an unidentified gram-negative bacillus. The term Flavobacterium meningosepticum for that organism was proposed by King in 1959 in her study of a group of previously unclassified bacteria associated with meningitis in infants. The term Flavobacterium—“yellow bacteria”—describes the yellow pigment often associated with members of this genus and meningosepticum describes the strains associated with infant meningitis. Although F. meningosepticum is not commonly considered a human pathogen, it has caused a variety of nosocomial infections including meningitis, postoperative bacteremia, and endocarditis. Most hospital outbreaks of F. meningosepticum infection involve meningitis in newborns and have been linked to environmental sources, mainly water-containing equipment. These outbreaks of neonatal meningitis tend to be severe with a high mortality rate and serious neurological sequelae in surviving patients.

Type
Original Articles
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1984

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References

1.Shulman, BH, Johnson, MS, A case of meningitis in a premature infant due to a proteolytic gram-negative bacillus. J Lab Clin Med 1944;29:500507.Google Scholar
2.King, EO, Studies on a group of previously unclassified bacteria associated with meningitis in infants. Am J Clin Pathol 1959;31:241247.CrossRefGoogle ScholarPubMed
3.Abrutyn, E, Plotkin, S, Flavobacterium meningosepticum and Alcaligenes faecalis meningitis: A review, in von Gravenitz, A, Sail, T (eds): Pathogenic Microorganisms from Atypical Clinical Sources. New York, Marcel Dekker Inc, 1973, pp 113123.Google Scholar
4.Altmann, G, Bogokovsky, B, In-vitro sensitivity of Flavobacterium meningosepticum to antimicrobial agents. J Med Microbiol 1971;4:296299.Google Scholar
5.Ferlauto, JJ, Wells, DH, Flavobacterium meningosepticum in the neonatal period. South Med J 1981;74:757759.Google Scholar
6.Plotkin, SA, McKitrick, JC, Nosocomial meningitis of the newborn caused by a Flavobacterium. JAMA 1966;194196.Google Scholar
7.Harrington, SP, Perlino, CA, Flavobacterium meningosepticum sepsis: Disease due to bacteria with unusual antibiotic susceptibility. South Med J 1981;74:764766.CrossRefGoogle ScholarPubMed
8.Olson, HW, Fredricksen, C, Siboni, KE, Flavobacterium meningosepticum in 8 non-fatal cases of postoperative bacteremia. Lancet 1965;1:12941296.CrossRefGoogle Scholar
9.Schiff, J, Suter, LS, Gourley, RD, et al: Flavobacterium infection as a cause of bacterial endocarditis. Ann Intern Med 1961;55:499506.Google Scholar
10.Werthamer, S, Weiner, M, Subacute bacterial endocarditis due to Flavobacterium meningosepticum. Am J Clin Pathol 1971;57:410412.Google Scholar
11.Cabrera, HA, Davis, GH, Epidemic meningitis of the newborn caused by flavobacteria. Am J Bis Child 1961;101:289304.Google Scholar
12.Olson, H, A clinical analysis of 10 cases of postoperative infection with Flavobacterium meningosepticum. Dan Med Bull 1967;14:15.Google Scholar
13.Thong, ML, Puthucheary, SD, Lee, EL, Flavobacterium meningosepticum infection: An epidemiologic study in a newborn nursery. J Clin Pathol 1981;34:429433.Google Scholar
14.Centers for Disease Control. Laboratory aspects in the control of nosocomial infection. Flavobacterium sp. National Nosocomial Infections Study Quarterly Report Third & Fourth Quarters 1973, 1975;34.Google Scholar
15.Du Moulin, GC, Airway colonization by Flavobacterium in an intensive care unit. J Clin Microbiol 1979;10:155160.Google Scholar
16.Coyle-Gilchrest, MM, Crewe, P, Roberts, G, Flavobacterium meningosepticum in the hospital environment. J Clin Pathol 1976;29:824826.Google Scholar
17.Teres, D, ICU-acquired pneumonia due to Flavobacterium meningosepticum. JAMA 1974;228:732.Google Scholar
18.Hazuka, BT, Dajani, AS, Talbot, K, et al: Two outbreaks of Flavobacterium meningosepticum Type E in a neonatal intensive care unit. J Clin Microbiol 1977;6:450455.Google Scholar
19.Mani, RM, Kuruvila, KC, Batiwala, PM, et al: Flavobacterium meningosepticum as an opportunist. J Clin Pathol 1978;31:220222.CrossRefGoogle ScholarPubMed
20.Simmons, BP, Wong, ES, Guideline for prevention of nosocomial pneumonia, in Guidelines for Prevention and Control of Nosocomial Infections Manual. Centers for Disease Control. Springfield, Virginia, National Information Service, September 1982, pp 67.Google Scholar
21.Aber, RC, Wennersten, C, Moellering, RC, Antimicrobial susceptibility of flavobacteria. Antimicrob Agents Chemother 1978;14:483487.CrossRefGoogle ScholarPubMed
22.Hawley, HB, Gump, DW, Vancomycin therapy of bacterial meningitis. Am J Dis Child 1973;126:261264.Google Scholar