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Thirty-Day Laboratory-Based Surveillance for Carbapenem-Resistant Enterobacteriaceae in the Minneapolis-St. Paul Metropolitan Area

  • Edwin C. Pereira (a1), Kristin M. Shaw (a2), Paula M. Snippes Vagnone (a2), Jane E. Harper (a2), Alexander J. Kallen (a3), Brandi M. Limbago (a3) and Ruth Lynfield (a2)...

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) are a growing problem in the United States. We explored the feasibility of active laboratory-based surveillance of CRE in a metropolitan area not previously considered to be an area of CRE endemicity. We provide a framework to address CRE surveillance and to monitor changes in the incidence of CRE infection over time.

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Corresponding author

420 Delaware Street SE, MMC 250, Minneapolis, MN 55455 (pere0051@umn.edu)

References

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1. Centers for Disease Control and Prevention. Healthcare-associated infections (HAIs): tracking CRE. http://www.cdc.gov/hai/organisms/cre/TrackingCRE.html. Published luly 9, 2012. Accessed June 28, 2013.
2. Gupta, N, Limbago, BM, Patel, JB, Kallen, AJ. Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. Clin Infect Dis 2011;53(1):6067.
3. Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing: Twenty-Second Informational Supplement. Wayne, PA: CLSI, 2012. CLSI document M100-S22.
4. Centers for Disease Control and Prevention. Healthcare-associated infections (HAIs): multiplex real-time PCR detection of Klebsiella pneumoniae carbapenemase (KPC) and New Delhi metallo-β-lactamase (NDM-1) genes. http://www.cdc.gov/HAI/settings/lab/kpc-ndml-lab-protocol.html. Updated April 20, 2011. Accessed January 30, 2013.

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