Hostname: page-component-8448b6f56d-c47g7 Total loading time: 0 Render date: 2024-04-24T12:12:10.760Z Has data issue: false hasContentIssue false
  • English
  • Français

Standard versus combined chemical, mechanical, and heat decontamination of hospital drains harboring carbapenemase-producing organisms (CPOs): A randomized controlled trial

Published online by Cambridge University Press:  08 February 2021

Alainna J. Jamal Open the ORCID record for Alainna J. Jamal [Opens in a new window] ,
Rajni Pantelidis ,
Rachael Sawicki ,
Angel X. Li ,
Wayne Chiu ,
Deborah Morrison ,
John Marshman ,
Mahin Baqi ,
David Richardson  and
Allison J. McGeer
...Show all authors
Alainna J. Jamal
Affiliation:
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Sinai Health System, Toronto, Ontario, Canada
Rajni Pantelidis
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Rachael Sawicki
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Angel X. Li
Affiliation:
Sinai Health System, Toronto, Ontario, Canada
Wayne Chiu
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Deborah Morrison
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
John Marshman
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Mahin Baqi
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
David Richardson
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
Allison J. McGeer*
Affiliation:
Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Sinai Health System, Toronto, Ontario, Canada
Sergio Borgia
Affiliation:
William Osler Health System, Etobicoke and Brampton, Ontario, Canada
*
Author for correspondence: Allison J. McGeer, E-mail: allison.mcgeer@sinaihealth.ca
Get access Rights & Permissions [Opens in a new window]

Abstract

We sought to determine whether combined chemical, mechanical, and heat cleaning was superior to standard cleaning for the decontamination of 32 sink and shower drains harboring carbapenemase-producing organisms (CPOs). Of 16 intervention drains, 10 (63%) were decontaminated until day 7 versus 1 (5%) of 16 comparator drains (P = .002). Intensive cleaning may be useful if administered repeatedly in drain-associated CPO outbreaks.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 42 , Issue 10 , October 2021 , pp. 1275 - 1278
Check for updates
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

PREVIOUS PRESENTATION. Preliminary data were accepted for presentation at the CDC/SHEA Decennial Meeting (abstract no. 741) scheduled for March 2020; the meeting was cancelled due to COVID-19.

References

Nordmann, P, Naas, T, Poirel, L. Global spread of carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis 2011;17:1791–1798.CrossRefGoogle ScholarPubMed
Kizny Gordon, AE, Mathers, AJ, Cheong, EYL, et al. The hospital water environment as a reservoir for carbapenem-resistant organisms causing hospital-acquired infections—a systematic review of the literature. Clin Infect Dis 2017;64:1436–1444.CrossRefGoogle ScholarPubMed
Carling, PC. Wastewater drains: epidemiology and interventions in 23 carbapenem-resistant organism outbreaks. Infect Control Hosp Epidemiol 2018;39:972–979.CrossRefGoogle ScholarPubMed
Parkes, LO, Hota, SS. Sink-related outbreaks and mitigation strategies in healthcare facilities. Curr Infect Dis Rep 2018;20(10):42.CrossRefGoogle ScholarPubMed
Jamal, AJ, Garcia-Jeldes, F, Baqi, M, et al. Infection prevention and control practices related to carbapenemase-producing Enterobacteriaceae (CPE) in acute-care hospitals in Ontario, Canada. Infect Control Hosp Epidemiol 2019;40:1006–1012.CrossRefGoogle ScholarPubMed
Jamal, AJ, Mataseje, L, Brown, K, et al. Carbapenemase-producing Enterobacterales (CPE) in hospital drains in Ontario, Canada. J Hosp Infect 2020;106:820–827.CrossRefGoogle ScholarPubMed
Tijet, N, Patel, S, Melano, RG. Detection of carbapenemase activity in Enterobacteriaceae: comparison of the carbapenem inactivation method versus the Carba NP test. J Antimicrob Chemother 2016;71:274–276.CrossRefGoogle ScholarPubMed
M100 Performance Standards for Antimicrobial Susceptibility Testing, 29th Edition. Clinical and Laboratory Standards Institute website. https://clsi.org/media/2663/m100ed29_sample.pdf. Published 2019. Accessed June 15, 2020.Google Scholar
Grabowski, M, Lobo, JM, Gunnell, B, et al. Characterizations of handwashing sink activities in a single hospital medical intensive care unit. J Hosp Infect 2018;100:e115–e122.CrossRefGoogle Scholar
Kotay, S, Chai, W, Guilford, W, Barry, W, Barry, K, Mathers, A. Spread from the sink to the patient: in situ study using green fluorescent protein (GFP)-expressing Escherichia coli to model bacterial dispersion from hand-washing sink-trap reservoirs. Appl Env Microbiol 2017;83:1–12.CrossRefGoogle ScholarPubMed
Supplementary material: Image

Jamal et al. supplementray material

Figure S1

Download Jamal et al. supplementray material(Image)
Image 382.4 KB