Skip to main content Accessibility help

Response to Alert on Possible Infections with Mycobacterium chimaera From Contaminated Heater-Cooler Devices in Hospitals Participating in the Canadian Nosocomial Infection Surveillance Program (CNISP)

  • Dominik Mertz (a1) (a2), Jennifer Macri (a3), Susy Hota (a4) (a5), Kanchana Amaratunga (a6) (a7), Ian Davis (a8) (a9), Lynn Johnston (a8) (a9), Bonita Lee (a10) (a11), Linda Pelude (a6), Michelle Science (a12) (a13), Stephanie Smith (a11) (a14), Alice Wong (a15) (a16) and the Canadian Nosocomial Infection Surveillance Program (CNISP)...


Canadian hospitals were made aware of the risk of Mycobacterium chimaera infection associated with heater-cooler units (HCUs) through alerts issued by the US food and Drug Administration (FDA) and the US Centers for Disease Control and Prevention (CDC). In response, most hospitals conducted retrospective reviews for infections, informed exposed patients, and initiated a requirement for informed consent with HCU use.

Infect Control Hosp Epidemiol 2018;39:482–484


Corresponding author

Address correspondence to Dr Dominik Mertz, MD, MSc, Juravinski Hospital and Cancer Center, 711 Concession Street, Section M, Level 1, Room 3, Hamilton, ON, Canada, L8V 1C3 (


Hide All
1. van Ingen, J, Kohl, TA, Kranzer, K, et al. Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study. Lancet Infect Dis 2017;17:10331041.
2. Schreiber, PW, Sax, H. Mycobacterium chimaera infections associated with heater-cooler units in cardiac surgery. Curr Opin Infect Dis 2017;30:388394.
3. CDC Health Advisory. CDC advises hospitals to alert patients at risk from contaminated heater-cooler devices used during cardiac surgery. HAN-00397. Centers for Disease Control and Prevention website. Published 2016. Accessed January 24, 2018.
4. Chand, M, Lamagni, T, Kranzer, K, et al. Insidious risk of severe Mycobacterium chimaera infection in cardiac surgery patients. Clin Infect Dis 2017;64:335342.
5. Marra, AR, Diekema, DJ, Edmond, MB. Mycobacterium chimaera infections associated with contaminated heater-cooler devices for cardiac surgery: outbreak management. Clin Infect Dis 2017;65:669674.
6. Haller, S, Holler, C, Jacobshagen, A, et al. Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016. Euro Surveill 2016;21(17). doi: 10.2807/1560-7917.ES.2016.21.17.30215.
7. Hamad, R, Noly, PE, Perrault, LP, Pellerin, M, Demers, P. Mycobacterium chimaera infection after cardiac surgery: first Canadian outbreak. Ann Thorac Surg 2017;104:e43e45.
8. Schreiber, PW, Kuster, SP, Hasse, B, et al. Reemergence of Mycobacterium chimaera in heater-cooler units despite intensified cleaning and disinfection protocol. Emerg Infect Dis 2016;22:18301833.
9. Nguyen, A, Hook, CC, Dearani, JA, Schaff, HV. Mycobacterium chimaera: the ethical duty to disclose the minimal risk of infection to exposed patients. J Thorac Cardiovasc Surg 2017;153:14221424 e1.


Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed