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Reducing Clostridium difficile Colitis Rates Via Cost-Saving Diagnostic Stewardship

  • Christina Yen (a1) (a2), Paul Holtom (a1) (a2), Susan M. Butler-Wu (a1) (a3), Noah Wald-Dickler (a1) (a2), Ira Shulman (a1) (a3) and Brad Spellberg (a1) (a2)...


We conducted a quality improvement project at a large public tertiary-care academic hospital to reduce reported hospital-acquired Clostridium difficile infection (CDI) rates. We introduced diagnostic stewardship and provider education, resulting in a 2-fold reduction in C. difficile nucleic acid amplification test (NAAT) orders and markedly lower hospital CDI rate.

Infect Control Hosp Epidemiol 2018;39:734–736


Corresponding author

Address correspondence to Brad Spellberg, MD, 2051 Marengo Street, Los Angeles, CA 90033 (


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