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Reactive Infection Control Strategy for Control of New Delhi Metallo-β-Lactamase (NDM)-Producing Enterobacteriaceae Analyzed Using Whole-Genome Sequencing: Hits and Misses

  • Kalisvar Marimuthu (a1) (a2), Oon Tek Ng (a1), Wei Xin Khong (a1), Eryu Xia (a3), Yik-Ying Teo (a3) (a4) (a5) (a6) (a7), Rick Twee-Hee Ong (a4), David Chien Lye (a1) (a2), Angela Liping Chow (a8), Prabha Krishnan (a9) and Brenda Sze Ang (a1)...


Genetically distinct isolates of New Delhi metallo-β-lactamase (NDM)–producing Enterobacteriaceae were identified from the clinical cultures of 6 patients. Screening of shared-ward contacts identified 2 additional NDM-positive patients. Phylogenetic analysis proved that 1 contact was a direct transmission while the other was unrelated to the index, suggesting hidden routes of transmission.

Infect Control Hosp Epidemiol 2016;37:987–990


Corresponding author

Address correspondence to Kalisvar Marimuthu, Department of Infectious Diseases, 11 Jalan Tan Tock Seng, 308433 Singapore (


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PREVIOUS PRESENTATION. The Third International Conference on Prevention and Infection Control (ICPIC) in Geneva, Switzerland on June 13, 2015.


Authors with equal contribution.



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