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Randomized Controlled Trial to Determine the Impact of Probiotic Administration on Colonization With Multidrug-Resistant Organisms in Critically Ill Patients

  • Jennie H. Kwon (a1), Kerry M. Bommarito (a1), Kimberly A. Reske (a1), Sondra M. Seiler (a1), Tiffany Hink (a1), Hilary M. Babcock (a1), Marin H. Kollef (a2), Victoria J. Fraser (a1), Carey-Ann D. Burnham (a3) and Erik R. Dubberke (a1)...

Abstract

This was a randomized controlled pilot study of Lactobacillus rhamnosus GG versus standard of care to prevent gastrointestinal multidrug-resistant organism colonization in intensive care unit patients. Among 70 subjects, there were no significant differences in acquisition or loss of any multidrug-resistant organisms (P>.05) and no probiotic-associated adverse events.

Infect. Control Hosp. Epidemiol. 2015;36(12):1451–1454

Copyright

Corresponding author

Address correspondence to Jennie H. Kwon, DO, Washington University School of Medicine, Division of Infectious Diseases, 6600 S Euclid Ave, Campus Box 8051, St. Louis, MO 63110 (JKwon@dom.wustl.edu).

References

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