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Novel KPC Variant from a Carbapenem-Resistant Strain of Klebsiella pneumoniae in a Chinese Hospital

  • Jian Ming Zhu (a1), Ru Jin Jiang (a1), Zu Huang Mi (a2), Hai Sheng Kong and Feng Zhang (a3)...
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      Novel KPC Variant from a Carbapenem-Resistant Strain of Klebsiella pneumoniae in a Chinese Hospital
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      Novel KPC Variant from a Carbapenem-Resistant Strain of Klebsiella pneumoniae in a Chinese Hospital
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Copyright

Corresponding author

Clinical Laboratory Department of the Third Affiliated Hospital, Nantong University, 585 Xing Yuan North Road, Wuxi 214041, China (zf9958@163.com)

References

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1. Yigit, H, Queenan, AM, Anderson, GJ, et al. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae . Antimicrob Agents Chemother 2001;45:11511161.
2. Yigit, H, Queenan, AM, Rasheed, JK, et al. Carbapenem-resistant strain of Klebsiella oxytoca harboring carbapenem-hydrolyzing beta-lactamase KPC-2. Antimicrob Agents Chemother 2003;47:38813889.
3. Endimiani, A, Perez, F, Bajaksouzian, S, et al. Evaluation of updated interpretative criteria for categorizing Klebsiella pneumoniae with reduced carbapenem susceptibility. J Clin Microbiol 2010;48:44174425.
4. Nordmann, P, Cuzon, G, Naas, T. The real threat of Klebsiell pneumoniae carbapenemase-producing bacteria. Lancet Infect Dis 2009;9:228236.
5. Cuzon, G, Naas, T, Truong, H, et al. Worldwide diversity of Klebsiella pneumoniae that produce beta-lactamase bla KPC-2 gene. Emerg Infect Dis 2010;16:13491356.
6. Zhang, R, Wang, XD, Cai, JC, et al. Outbreak of KPC-2-producing Klebsiella pneumoniae with high qnr prevalence in a Chinese hospital. J Med Microbiol 2011;60(7):977982.
7. Mataseje, LF, Boyd, DA, Willey, BM, et al. Plasmid comparison and molecular analysis of Klebsiella pneumoniae harbouring bla KPC from New York City and Toronto. J Antimicrob Chemother 2011;66:12731277.
8. Woodford, N, Tierno, PM Jr, Young, K, et al. Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class a beta-lactamase, KPC-3, in a New York medical center. Antimicrob Agents Chemother 2004;48:47934799.
9. Wolter, DJ, Kurpiel, PM, Woodford, N, Palepou, MF, Goering, RV, Hanson, ND. Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4. Antimicrob Agents Chemother 2009;53:557562.

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