Hostname: page-component-8448b6f56d-sxzjt Total loading time: 0 Render date: 2024-04-19T17:20:37.671Z Has data issue: false hasContentIssue false

Nosocomial Bacteremia in Perspective: A Community-Wide Study

Published online by Cambridge University Press:  02 January 2015

Eric R. Brenner
Affiliation:
Richland Memorial Hospital, Columbia, South Carolina University of South Carolina School of Medicine, Columbia, South Carolina
Charles S. Bryan*
Affiliation:
Richland Memorial Hospital, Columbia, South Carolina University of South Carolina School of Medicine, Columbia, South Carolina
*
ACC 2, Richland Memorial Hospital, Columbia, SC 29203

Abstract

Prospective surveillance of 1,527 episodes of bacteremia in the four major hospitals serving a community of 300,000 revealed striking differences among the hospitals. The rate of community-acquired bacteremia ranged from 1.9 to 6.8 per 1000 discharges; the rate of nosocomial bacteremia ranged from 0.9 to 9.8 per 1000 discharges. Death rates attributed to nosocomial bacteremias varied among the hospitals by as much as 40-fold. Nosocomial bacteremias were less frequent at two community non-teaching hospitals than at two teaching hospitals. Although fewer blood cultures were obtained at the nonteaching hospitals, the ratio of blood cultures obtained to deaths attributed to bacteremic infection was highest at these hospitals, suggesting that physicians recognized the importance of obtaining blood cultures in critically ill patients. The potential usefulness of bacteremia surveillance is reviewed. It is suggested that hospitals serving a single community might constitute an appropriate unit for such surveillance [Infect Control 1981: 2(3):219-226.]

Type
Original Articles
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1981

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Garner, JS, Bennett, JV, Scheckler, WE, et al.Surveillance of nosocomial infections. In: Proceedings of the International Conference on Nosocomial Infections, Center for Disease Control, August 3-6, 1970. Chicago, American Hospital Association, 1971:277–81.Google Scholar
2.McGowan, JE Jr, Barnes, MW, Finland, M. Bacteremia at Boston City Hospital: Occurrence and mortality during 12selected years (1935-1972), with special reference to hospital-acquired cases. J Infect Dis 1975;132:315–35.CrossRefGoogle Scholar
3.Aber, RC. Bennett, JV. Surveillance of nosocomial infections. In: Bennett, JV. Brachman, PS (eds). Hospital Infections. Boston, Little. Broun. 1979:5361.Google Scholar
4.MrCabe, WR. Jackson, GG. Gram-negative bacteremia. I. Etiology and ecology. Arch Intern Med 1962:110:817–64.Google Scholar
5.Britt, MR. Schleupner, CJ, Mitsumiya, S. Severity of underlying disease as a predictor of nosocomial infection. JAMA 1978;239:1047–51.CrossRefGoogle ScholarPubMed
6.VS Personal Computing (VSPC). General I'ser's Guide and Command Language, ed's. IBM. 1978.Google Scholar
7.SAS I'ser's Guide. Gary. North Carolina. SAS Institute. 1979.Google Scholar
8.Bryan, CS. Parker, E. Schoenlein, PV, et al.Plasmidmediated antibiotic resistance in a changing hospital environment. Efficacy of control measures. Am J Infect Control 1980:8:6571.CrossRefGoogle Scholar
9.Martin, CM. A national bacteremia registry (editorial). J Infect Dis 1969:120:4956.CrossRefGoogle Scholar
10.Center for Disease Control. National Nosocomial Infections Study Report. 1977 (6-Month Summaries). Issued November 1979:215.Google Scholar
11.Scheckler, WE. Septicemia in a community hospital 1970 through 1973. JAMA 1977:237:1938–41.CrossRefGoogle Scholar
12.McGowan, JE Jr. Bacteremia in the hospitalized patient: A focus for infection control (editorial). Arch Intern Med 1977:137:1670.CrossRefGoogle Scholar
13.Schaberg, DR, Alford, RH. Anderson, Ret al.An outbreak of nosocomial infection due to multiply resistant Serratia inarrescrns: Evidence of interhospital spread. J Infect Dis 1976:134:1818.CrossRefGoogle ScholarPubMed
14.Austrian, R. Pneumococcal vaccine: Developments and prospects (editorial). Amer J Med 1979;67:5479.CrossRefGoogle Scholar
15.McGowan, JF Jr. Parrot, PL. Duly, VP. Nosocomial bacteremia: Potential for prevention of procedure-related cases. JAMA 1977:237:2727–30.CrossRefGoogle ScholarPubMed
16.Holzman, RS. Florman, AL. Toharsky, B. The clinical usefulness of an ongoing bacteremia surveillance program. Am J Med Sci 1977:274:13–9.CrossRefGoogle ScholarPubMed
17.Myerowitz, RL. Medeiros, AA. O'Brien, TF. Recent experience with bacillemia due to gram-negative organisms. J Infect Dis 1971:124:239–45.CrossRefGoogle ScholarPubMed
18.Setia, V, Gross, PA. Bacteremia in a community hospital: Spectrum and mortality. Arch Intern Med 1977:137:1698–701.CrossRefGoogle Scholar
19.Spengler, RF. Greenough, WB III. Stolley, PD. A descriptive study of nosocomial bacteremias at The Johns Hopkins Hospital. 1968-1974. Johns Hopkins Med J 1978;142:7784.Google Scholar
20.Crosson, FJ Jr. Feder, HM, Bocchini, JAet al. Neonatal sepsis at The Johns Hopkins Hospital, 1969-1975. Bacterial isolates and clinical correlates. Johns Hopkins Med J 1977;140:3741.Google Scholar
21.Dobkin, JF, Miller, MH, Steigbigel, NH. Septicemia in patiems on chronic hemodialysis. Ann Intern Med 1978;88:2833.CrossRefGoogle Scholar
22.Dorand, RD, Cook, LN, Andrews, BF. Incidence of sepsis in neonates with clinical respiratory distress. South Med J 1979;72:12624.CrossRefGoogle ScholarPubMed
23.Favor, LF, Tarpay, M. Blackstock, R. Septicemia in children with cancer. South Med J 1979;72:1325.CrossRefGoogle ScholarPubMed
24.Kilton, LJ, Fossieck, BE Jr, Cohen, MH, et al.Bacteremia due to gram-positive cocci in patients with neoplastic disease. Am J Med 1979:66:596–602.CrossRefGoogle ScholarPubMed
25.Mayhall, CG, Lamb, VA, Gayle, WE Jr, et al. Enterobacter cloacae septicemia in a burn center: Epidemiology and control of an outbreak. J Infect Dis 1979;139:166–70.CrossRefGoogle Scholar
26.Freeman, J, McGowan, JE Jr. Risk factors for nosocomial infection. J Infect Dis 1978;138:8119.CrossRefGoogle ScholarPubMed
27.Svanbom, M. Septicemia, I. A prospective study on etiology underlying factors and sources of infection. Scand J Infect Dis 1979;11:187–98.CrossRefGoogle ScholarPubMed
28.Band, JD, Maki, DG. Infections caused by arterial catheters used for hemodynamic monitoring. Am J Med 1979;67:735–41.CrossRefGoogle ScholarPubMed
29.Felts, SK, Schaffner, W, Melly, MA, et al.Sepsis caused by contaminated intravenous fluids: Epidemiologic, clinical, and laboratory investigation of an outbreak in one hospital. Ann Intern Med 1972;77:881–90.CrossRefGoogle ScholarPubMed
30.Klaslow, RA, Mackel, DC, Mallison, GF. Nosocomial pseudobacteremia: Positive blood cultures due to contaminated benzalkonium antiseptic. JAMA 1976;236:24079.CrossRefGoogle Scholar
31.Kiani, D, Quirin, EL, Burch, KH, et al.The increasing importance of polymicrobial bacteremia. JAMA 1979;242:10447.CrossRefGoogle ScholarPubMed
32.Lee, BK, Grossley, K, Gerding, DN. The association between Staphylococcus aureus bacteremia and bacieriuria. Am J Med 1978;65:3036.CrossRefGoogle Scholar
33.Young, LS, Martin, WJ, Meyer, RD, et al.Gram-negative rod bacteremia: Microbiologic, immunologic, and therapeutic considerations. Ann Intern Med 1977;86:456–71.CrossRefGoogle ScholarPubMed
34.Ho, PWL, Pien, FD, Hamburg, D. Value of cultures in patients with acute cellulitis. South Med J 1979;72:14023.CrossRefGoogle ScholarPubMed
35.Guerrant, RL, Strausbaugh, LJ, Wenzel, RP, et al.Nosocomial bloodstream infections caused by gentamicin-resistant gram-negative bacilli. Am J Med 1977;62:894–901.CrossRefGoogle ScholarPubMed
36.McGowan, JE Jr, Gamer, G, Wilcox Getal, Antibioticsusceptibility of gram-negative bacilli isolated from blood cultures: Results of tests with 35 agents and strains from 169 patients at Boston City Hospital during 1972. Am J Med 1979:2258.Google Scholar
37.Galpin, JE, Chow, AW, Bayer, AS, et al.Sepsis associated with decubitus ulcers. Am J Med 1976:61:316–50.CrossRefGoogle ScholarPubMed
38.Rose, R. Hunting, K. Townsend TReial. Morbidity mortality and economics of hospital-acquired blood stream infections: A controlled study. South Med J 1977:70:12679.CrossRefGoogle ScholarPubMed
39.Spengler, RF, Greenough, WB III. Hospital costs and mortality attributed to nosocomial bacteremias. JAMA 1978;240:24558.CrossRefGoogle ScholarPubMed
40.Flick, MR, Guff, LE. Pseudomonas bacteremia: Review of 108 cases. Am J Med 1976;60:5018.CrossRefGoogle ScholarPubMed