Hostname: page-component-76fb5796d-dfsvx Total loading time: 0 Render date: 2024-04-25T12:57:03.441Z Has data issue: false hasContentIssue false

Management of an Outbreak of Vancomycin-Resistant Enterococci in the Medical Intensive Care Unit of a Cancer Center

Published online by Cambridge University Press:  02 January 2015

Hend Hanna*
Affiliation:
Section of Infection Control, Department of Internal Medicine Specialties, The University of Texas M.D. Anderson Cancer Center, Houston, Texas
Jan Umphrey
Affiliation:
Section of Infection Control, Department of Internal Medicine Specialties, The University of Texas M.D. Anderson Cancer Center, Houston, Texas
Jeffrey Tarrand
Affiliation:
Section of Infection Control, Department of Internal Medicine Specialties, The University of Texas M.D. Anderson Cancer Center, Houston, Texas
Michelle Mendoza
Affiliation:
Section of Infection Control, Department of Internal Medicine Specialties, The University of Texas M.D. Anderson Cancer Center, Houston, Texas
Issam Raad
Affiliation:
Section of Infection Control, Department of Internal Medicine Specialties, The University of Texas M.D. Anderson Cancer Center, Houston, Texas
*
The University of Texas M.D. Anderson Cancer Center, Section of Infection Control—Box 47, 1515 Holcombe Blvd. Houston, TX 77030

Abstract

Between November 1996 and February 1997, 17 episodes of vancomycin-resistant enterococci (VRE) infection or colonization (9 infections, 8 colonizations), all with the same or a similar genomic DNA pattern, were identified in the medical intensive care unit (MICU) of a tertiary-care cancer hospital. The cases were genotypically traced to a patient who was admitted to the hospital in September 1996 and who, by December 1996, had four different admissions to the MICU. Multifaceted infection control measures, including decontamination of the environment and of nondisposable equipment, halted the nosocomial transmission of VRE in the MICU.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Uttley, AH, Collins, CH, Naidoo, J, George, RC. Vancomycin-resistant enterococci. Lancet 1988;1:5758.Google Scholar
2. Centers for Disease Control. Nosocomial enterococci resistant to vancomycin—United States, 1989-1993. MMWR 1993;42:597599.Google Scholar
3. Murray, BE. Vancomycin-resistant enterococcal infections. N Engl J Med 2000;342:710721.Google Scholar
4. Facklam, RR, Sahm, DF. Enterococcus. In: Manual of Clinical Microbiology. 6th ed. 1995:308314.Google Scholar
5. Murray, BE, Singh, SV, Heath, JD, Sharma, BR, Weinstock, GM. Comparison of genomic DNAs of different enterococcal isolates using restriction endonucleases with infrequent recognition sites. J Clin Microbiol 1990;29:20592063.Google Scholar
6. Ostrowsky, BE, Venkataraman, L, D'Agata, EM, Gold, HS, DeGirolami, PC, Samore, MH. Vancomycin-resistant enterococci in intensive care units: high frequency of stool carriage during a non-outbreak period. Arch Intern Med 1999;159:14671472.Google Scholar
7. Singh-Naz, N, Sleemi, A, Pikis, A, Patel, KM, Campos, JM. Vancomycin-resistant Enterococcus faecium colonization in children. J Clin Microbiol 1999;37:413416.Google Scholar
8. Schuster, F, Graubner, UB, Schmid, I, Weiss, M, Belohradsky, BH. Vancomycin-resistant enterococci—colonization of 24 patients on a pediatric oncology unit. Klin Padiatr 1998;210:261263.CrossRefGoogle ScholarPubMed
9. Austin, DJ, Bonten, MJ, Weinstein, RA, Slaughter, S, Anderson, RM. Vancomycin-resistant enterococci in intensive-care hospital settings: transmission dynamics, persistence, and the impact of infection control programs. Proc Natl Acad Sci USA 1999;96:69086913.Google Scholar
10. Montecalvo, MA, Jarvis, WR, Uman, J, Shay, DK, Petrullo, C, Rodney, K, et al. Infection-control measures reduce transmission of vancomycin-resistant enterococci in an endemic setting. Ann Intern Med 1999;131:269272.CrossRefGoogle Scholar
11. Recommendations for preventing the spread of vancomycin resistance. Hospital Infection Control Practices Advisory Committee (HICPAC). Infect Control Hosp Epidemiol 1995;16:105113.Google Scholar
12. Wendt, C, Wiesenthal, B, Dietz, E, Ruden, H. Survival of vancomycin-resistant and vancomycin-susceptible enterococci on dry surfaces. J Clin Microbiol 1998;36:37343736.Google Scholar
13. Moellering, RC. Vancomycin-resistant enterococci. Clin Infect Dis 1998;26:11961199.CrossRefGoogle ScholarPubMed