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Low Incidence of Clostridium difficile Infection (CDI) in Patients Treated with Outpatient Parenteral Antimicrobial Therapy (OPAT)

  • Ken K. Wong (a1), Thomas G. Fraser (a1), Nabin K. Shrestha (a1), Cynthia Fatica (a2) and Abhishek Deshpande (a1) (a3)...
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      Low Incidence of Clostridium difficile Infection (CDI) in Patients Treated with Outpatient Parenteral Antimicrobial Therapy (OPAT)
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Abstract

Copyright

Corresponding author

Address correspondence to Abhishek Deshpande, MD, PhD, Medicine Institute Center for Value Based Care Research, 9500 Euclid Avenue, Desk G10, Cleveland Clinic, Cleveland, OH 44195 (abhishekdp@gmail.com).

References

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1.Tice, AD, Rehm, SJ, Dalovisio, JR, et al. Practice guidelines for outpatient parenteral antimicrobial therapy. IDSA guidelines. Clin Infect Dis 2004;38:16511672.
2.Gordon, SM, Shrestha, NK, Rehm, SJ. Transitioning antimicrobial stewardship beyond the hospital: the cleveland clinic's community-based parenteral anti-infective therapy (CoPAT) program. J Hosp Med 2011;6 Suppl 1:S24S30.
3.Chapman, AL, Dixon, S, Andrews, D, Lillie, PJ, Bazaz, R, Patchett, JD. Clinical efficacy and cost-effectiveness of outpatient parenteral antibiotic therapy (OPAT): A UK perspective. J Antimicrob Chemother 2009;64:13161324.
4.Barr, DA, Semple, L, Seaton, RA. Outpatient parenteral antimicrobial therapy (OPAT) in a teaching hospital-based practice: a retrospective cohort study describing experience and evolution over 10 years. Int J Antimicrob Agents 2012;39:407413.
5.Lane, MA, Marschall, J, Beekmann, SE, et al. Outpatient parenteral antimicrobial therapy practices among adult infectious disease physicians. Infect Control Hosp Epidemiol 2014;35:839844.
6.Kutty, PK, Woods, CW, Sena, AC, et al. Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA. Emerg Infect Dis 2010;16:197204.
7.Cohen, SH, Gerding, DN, Johnson, S, et al. Clinical practice guidelines for clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of america (SHEA) and the infectious diseases society of america (IDSA). Infect Control Hosp Epidemiol 2010;31:431455.
8.Samore, MH, DeGirolami, PC, Tlucko, A, Lichtenberg, DA, Melvin, ZA, Karchmer, AW. Clostridium difficile colonization and diarrhea at a tertiary care hospital. Clin Infect Dis 1994;18:181187.
9.Jury, LA, Sitzlar, B, Kundrapu, S, et al. Outpatient healthcare settings and transmission of clostridium difficile. PLoS One 2013;8:e70175.
10.Deshpande, A, Pant, C, Pasupuleti, V, et al. Association between proton pump inhibitor therapy and clostridium difficile infection in a meta-analysis. Clin Gastroenterol Hepatol 2012;10:225233.

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