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Laxative Use in the Setting of Positive Testing for Clostridium difficile Infection

  • Syed M. Ahmad (a1), Natalia Blanco (a2), Courtney M. Dewart (a3), Anna Dobosz (a1) and Anurag N. Malani (a1) (a4)...
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Abstract

Copyright

Corresponding author

Address correspondence to Anurag N. Malani, MD, 5333 McAuley Drive, Suite 6007, Ypsilanti, MI 48197 (Anurag.Malani@stjoeshealth.org).

Footnotes

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PREVIOUS PRESENTATION. Select data and findings were accepted as a poster (abstract no. 352) at the Society for Healthcare Epidemiology of America Spring 2017 Conference in St. Louis, Missouri on March 30, 2017.

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References

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1. Magill, SS, Edwards, JR, Bamberg, W, et al. Multistate point-prevalence survey of health care-associated infections. N Engl J Med 2014;370:11981208.
2. Lessa, FC, Mu, Y, Bamberg, WM, et al. Burden of Clostridium difficile infection in the United States. N Engl J Med 2015;372:825834.
3. Buckel, WR, Avdic, E, Carroll, KC, Gunaseelan, V, Hadhazy, E, Cosgrove, SE. Gut check: Clostridium difficile testing and treatment in the molecular testing era. Infect Control Hosp Epidemiol 2015;36:217221.
4. Alasmari, F, Seiler, SM, Hink, T, Burnham, CA, Dubberke, ER. Prevalence and risk factors for asymptomatic Clostridium difficile carriage. Clin Infect Dis 2014;59:216222.
5. Polage, CR, Gyorke, CE, Kennedy, MA, et al. Overdiagnosis of Clostridium difficile infection in the molecular test era. JAMA Intern Med 2015;175:17921801.
6. Polage, CR, Chin, DL, Leslie, JL, Tang, J, Cohen, SH, Solnick, JV. Outcomes in patients tested for Clostridium difficile toxins. Diagn Microbiol Infect Dis 2012;74:369373.
7. Tehrani, L, Seville, MT. Laxative use and Clostridium difficile testing and treatment. In: Program and abstracts of the Annual Scientific Meeting of the Infectious Diseases Society of America (IDWeek); October 7–11, 2015; San Diego, CA. Abstract no. 956.
8. Rineer, S, Dizon, J, Logan, J, Hsu, V. Laxative use and testing delays may overestimate the true burden of Clostridium difficile. In: Program and abstracts of the Annual Scientific Meeting of the Infectious Diseases Society of America (IDWeek); October 7–11, 2015; San Diego, CA. Abstract no. 955.
9. Truong, CY, Gombar, S, Wilson, R, et al. Real-time electronic tracking of diarrheal episodes and laxatives therapy enables verification of Clostridium difficile clinical testing criteria and reduction of Clostridium difficile infection rates. J Clin Microbiol 2017;55:12761284.
10. Polage, CR, Solnick, JV, Cohen, SH. Nosocomial diarrhea: evaluation and treatment of causes other than Clostridium difficile . Clin Infect Dis 2012;55:982989.

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