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Knowledge, Attitudes, and Practices Regarding Antimicrobial Use and Stewardship Among Prescribers at Acute-Care Hospitals

  • Elizabeth Salsgiver (a1), Daniel Bernstein (a1), Matthew S. Simon (a1) (a2), Daniel P. Eiras (a1), William Greendyke (a3), Christine J. Kubin (a2) (a3), Monica Mehta (a2), Brian Nelson (a2), Angela Loo (a2), Liz G. Ramos (a2), Haomiao Jia (a3), Lisa Saiman (a2) (a3), E. Yoko Furuya (a2) (a3) and David P. Calfee (a1) (a2)...

Abstract

OBJECTIVE

To assess antimicrobial prescriber knowledge, attitudes, and practices (KAP) regarding antimicrobial stewardship (AS) and associated barriers to optimal prescribing.

DESIGN

Cross-sectional survey.

SETTING

Online survey.

PARTICIPANTS

A convenience sample of 2,900 US antimicrobial prescribers at 5 acute-care hospitals within a hospital network.

INTERVENTION

The following characteristics were assessed with an anonymous, online survey in February 2015: attitudes and practices related to antimicrobial resistance, AS programs, and institutional AS resources; antimicrobial prescribing and AS knowledge; and practices and confidence related to antimicrobial prescribing.

RESULTS

In total, 402 respondents completed the survey. Knowledge gaps were identified through case-based questions. Some respondents sometimes selected overly broad therapy for the susceptibilities given (29%) and some “usually” or “always” preferred using the most broad-spectrum empiric antimicrobials possible (32%). Nearly all (99%) reported reviewing antimicrobial appropriateness at 48–72 hours, but only 55% reported “always” doing so. Furthermore, 45% of respondents felt that they had not received adequate training regarding antimicrobial prescribing. Some respondents lacked confidence selecting empiric therapy using antibiograms (30%), interpreting susceptibility results (24%), de-escalating therapy (18%), and determining duration of therapy (31%). Postprescription review and feedback (PPRF) was the most commonly cited AS intervention (79%) with potential to improve patient care.

CONCLUSIONS

Barriers to appropriate antimicrobial selection and de-escalation of antimicrobial therapy were identified among front-line prescribers in acute-care hospitals. Prescribers desired more AS-related education and identified PPRF as the most helpful AS intervention to improve patient care. Educational interventions should be preceded by and tailored to local assessment of educational needs.

Infect Control Hosp Epidemiol 2018;39:316–322

Copyright

Corresponding author

Address correspondence to David P. Calfee, MD, MS, Weill Cornell Medicine, 525 East 68th Street, Box 265, New York, NY 10065 (dpc9003@med.cornell.edu).

Footnotes

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PREVIOUS PRESENTATION. An abstract summarizing the results of this study was presented as a poster at the national conference, IDWeek 2015 on October 8, 2015 in San Diego, California (abstract #204).

Footnotes

References

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