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Knowledge, Attitudes, and Behaviors Regarding Piperacillin-Tazobactam Prescribing Practices: Results From a Multicenter Study

  • Theresa L. Antoine (a1), Amy B. Curtis (a1) (a2), Henry M. Blumberg (a3) (a4), Kathryn DeSilva (a5), Mesfin Fransua (a3) (a6), Carolyn V. Gould (a7) (a4), Mark King (a3) (a4) (a8), Alice A. Kraman (a7), Jan Pack (a9), Bruce Ribner (a9) (a4), Ulrich Seybold (a3) (a4), James P. Steinberg (a7) (a4), Jane B. Wells (a3), Ronda L. Sinkowitz-Cochran (a1), Denise Cardo (a1), John A. Jernigan (a1) (a4) and Robert P. Gaynes (a5) (a4)...


We investigated knowledge, attitudes, and behaviors of prescribers concerning piperacillin-tazobactam use at 4 Emory University-affiliated hospitals. Discussions during focus groups indicated that the participants' perceived knowledge of clinical criteria for appropriate piperacillin-tazobactam use was inadequate. Retrospective review of medical records identified inappropriate practices. These findings have influenced ongoing interventions aimed at optimizing piperacillin-tazobactam use.


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1.Brinsley, K, Srinivasan, A, Sinkowitz-Cochran, R, et al. Implementation of the campaign to prevent antimicrobial resistance in healthcare settings: 12 steps to prevent antimicrobial resistance among hospitalized adults— experiences from 3 institutions. Am J Infect Control 2005; 33:5354.
2.Monnet, DL, Archibald, LK, Phillips, L, Tenover, FC, McGowan, JE Jr, Gaynes, RP. Antimicrobial use and resistance in eight US hospitals: complexities of analysis and modeling. Intensive Care Antimicrobial Resistance Epidemiology Project and National Nosocomial Infections Surveillance System Hospitals. Infect Control Hosp Epidemiol 1998; 19:388394.
3.Krueger, RA. Focus Groups: A Practical Guide for Applied Research. 2nd ed. Thousand Oaks, CA: Sage Publications; 1994.
4.Mandell, LA, Bartlett, JG, Dowell, SF, File, TM Jr, Musher, DM, Whitney, C. Update of practice guidelines for the management of communityacquired pneumonia in immunocompetent adults. Clin Infect Dis 2003; 37:14051433.
5.National Nosocomial Infections Surveillance (NNIS) System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 2004; 32:470485.
6.Solomkin, JS, Mazuski, JE, Baron, EJ, et al. Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections. Clin Infect Dis 2003;37:9971005.
7.Lipsky, BA, Berendt, AR, Deery, HG, et al. Diagnosis and treatment of diabetic foot infections. Clin Infect Dis 2004; 39:885910.
8.Goldmann, DA, Weinstein, RA, Wenzel, RP, et al. Strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in hospitals: a challenge to hospital leadership. JAMA 1996; 275:234240.


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