Hostname: page-component-8448b6f56d-qsmjn Total loading time: 0 Render date: 2024-04-20T00:19:29.448Z Has data issue: false hasContentIssue false

Interpretation and Use of the Western Blot Assay for Serodiagnosis of Human Immunodeficiency Virus Type 1 Infections*

Published online by Cambridge University Press:  21 June 2016

Association of State and Territorial Public Health Laboratory Directors
Affiliation:
Association of State and Territorial Public Health Laboratory Directors, Centers for Disease Control (CDC), Atlanta, Georgia

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Fourth Consensus Conference
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

*

Originally appeared in MMWR 1989; 38:1-6.

References

1.Centers for Disease Control: Provisional public health service interagency recommendations for screening donated blood and plasma tor antibody to the virus causing acquired immunodeficiency syndrome. MMWR 1985; 34:15.Google Scholar
2.Centers for Disease Control: Public health service guidelines for coun-selingand antibodv testing to prevent HIV infection and AIDS. MMWR 1987; 36:509515.Google Scholar
3.Centers for Disease Control Update: Serologic testing for antibody to human immunodeficiency virus. MMWR 1988; 36:833-840, 845.Google Scholar
4.Lange, JMA, Coulinho, RA, Krone, WJA, et al: Distinct IgG recognition patterns during progression of subclinical and clinical infection with lymphadenopathy associated virus/human T lymphotropic virus. Brit Med J 1986: 292:228230.Google Scholar
5.Esteban, JI, Shih, JW, Tai, CC, et al: Importance of Western blot analysis in predicting infectivity of anti-HTLV-III/LAV positive blood. Lancet 1985; ii: 18031806.Google Scholar
6.Goudsmit, J, Lange, JMA, Paul, DA. et al: 1987. Antigenemia and antibody titers to core and envelope antigens in AIDS, AIDS-related complex, and subclinical human immunodeficiency virus infection. J Infect Dis 1987; 155:558560.Google Scholar
7.Lauge, JMA, Paul, DA, Huisman, HG, et al: Persistent HIV antigenemia and decline of HIV core antibodies associated with transition to AIDS. Brit Med J 1986; 293:14591462.Google Scholar
8.Weber, JN, Clapham, PR. Weiss, RA, et al: Human immunodeficiency virus infection in two cohorts of homosexual men: Neutralizing sera and association of anti-gag antibody with prognosis. Lancet 1987; i:119121.Google Scholar
9.McDougal, JS, Kennedy, MS, Nicholson, JKA, et al: Antibody response to human immunodeficiency virus in homosexual men: Relation of antibody specificity, titer and isotype to clinical status, severity of immunodeficiency and disease progression. J Clin Invest 1987: 80:316324.Google Scholar
10.Zolla-Pazner, S, Gorney, MK, Honnen, WJ, et al: Reinterpretation of HIV Western blot patterns, N Engl J Med 1989, 320:12801281.Google Scholar
11.Pinter, A, Honnen, WJ, Tilley, A, et al: Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus (HIV-1). J Virology 1989, 63:26742679.Google Scholar
12.Du Pont Diagnostics: Human Immunodeficiency Virus (HIV): Biotech/DuFont HIV Western Blot Kit for Detection of Antibodies to HIV. Wilmington, Del, Du Pont Diagnostics, 1987.Google Scholar
13.Committee on HIV: Special update: Third Consensus Conference on HIV Testing. Association of State and Territorial Public Health Laboratory Directors. Infect Control Hasp Epidemiol 1988; 9:345349.Google Scholar
14.The Consortium for Retrovirus Serology Standardization. Serological diagnosis of human immunodeficiency virus infection by Western blot testing. JAMA 1988:260:674679.Google Scholar
15.Sandler, SC., Dodd, RY, Tang, CT: Diagnostic tests for HIV infection: Serology, in DeVita Vita, VT, Hellman, S, Rosenberg, SA (etls): AIDS: Etiology, Treatment, and Prevention, ed 2. Philadelphia, J.B. Lippincott, 1988.Google Scholar
16.Committee on HIV: Report and Recommendations. Fourth Consensus Conference on HIV Testing. Association of State and lerritorial Public Health Laboratory Directors. McLean, Va, March 1989.Google Scholar
17.Tang, C. Le, P. Mallory, D, et al: Western blot patterns of antibodies to human immunodeficiency virus (HIV). Transfusion 1988; 27:539.Google Scholar
18.Dock, NL, Lamberson, HV, O'Brien, TA. et al: Evaluation of atypical human immunodeficiencv virus immunoblot reactivity in blood donors. Transfusion 1988; 28:412418.Google Scholar
19.Kleinman, S, Fitzpatrick, L, Secord, K, et al: Tollow-iip testing and notification of anti-HIV Western blot atypical (indeterminanl) donors. Transfusion 1988: 28:280282.Google Scholar
20.Groopnian, JE, Caiazzo, T, Thomas, MA, et al: Lack of evidence of prolonged human immunodeficiency virus infection before antibody seroconversion. Blood 1988; 71: 17521754.Google Scholar
21.Biberfeld, G. Bredberg-Raden, U, Bottiger, B, et al: Blood donor sera with false-positive Western blot reactions to human immunodeficiency virus, letter. Lancet 1986; 2:289290.Google Scholar
22.Courouce, A. Muller, J, Richard, D: False-positive Western blot reactions to human immunodeficiency virus in blood donors, letter. Lancet 1986; 2:921922.Google Scholar
23.Van der Poel, CT, Reesink, HW, Tersmette, T, et al: Blood donations reactive for HIV in Western blot, but non-reactive in culture and recipients of blood. Lancet 1986; 2:752753.Google Scholar
24.Schochetman, G. Ou, C-Y, Jones, W: Polymerase Chain Reaction. J Infect Dis 1988; 158:11541157.Google Scholar