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Infection prevention and control practices related to carbapenemase-producing Enterobacteriaceae (CPE) in acute-care hospitals in Ontario, Canada

  • Alainna J. Jamal (a1) (a2), Felipe Garcia-Jeldes (a2), Mahin Baqi (a3), Sergio Borgia (a3), Jennie Johnstone (a2) (a4), Kevin Katz (a5), Philipp Kohler (a2), Matthew P. Muller (a1) (a6), Allison J. McGeer (a1) (a2) and for the CPE Investigators of the Toronto Invasive Bacterial Diseases Network (a7)...

Abstract

Objective:

To determine infection prevention and control (IPAC) practices for carbapenemase-producing Enterobacteriaceae (CPE), an emerging threat, at acute-care hospitals in Ontario, Canada.

Design:

A descriptive cross-sectional survey.

Methods:

We surveyed IPAC directors and managers at all acute-care hospitals in Ontario, Canada, to gather information on IPAC practices related to CPE, including admission screening, other patient screening, environmental testing, use of precautions to prevent transmission, and outbreak management.

Results:

Of 116 acute-care hospitals, 105 (91%) responded. Admission screening included patients previously colonized or infected with CPE (n = 64, 61%), patients recently hospitalized outside of Canada (Indian subcontinent, n = 62, 59%; other countries, n = 56, 53%), and patients recently hospitalized in Canada (n = 22, 21%). Fifty-one hospitals (49%) screened patients for colonization during an outbreak. Almost all hospitals (n = 101, 96%) used precautions to prevent transmission from patients with CPE colonization or infection; most hospitals (n = 54, 53%) continued precautions indefinitely. Few hospitals (n = 19, 18%) performed environmental cultures. Eight hospitals (8%) reported at least 1 outbreak, and 6 hospitals (6%) reported transmission from sink or shower drains to patients.

Conclusions:

Variability in practices may result from lack of evidence and challenges in updating guidelines as evidence emerges. A coordinated approach to slow the emergence of CPE should be considered in our population.

Copyright

Corresponding author

Author for correspondence: Allison J. McGeer, Email: allison.mcgeer@sinaihealthsystem.ca

References

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Infection prevention and control practices related to carbapenemase-producing Enterobacteriaceae (CPE) in acute-care hospitals in Ontario, Canada

  • Alainna J. Jamal (a1) (a2), Felipe Garcia-Jeldes (a2), Mahin Baqi (a3), Sergio Borgia (a3), Jennie Johnstone (a2) (a4), Kevin Katz (a5), Philipp Kohler (a2), Matthew P. Muller (a1) (a6), Allison J. McGeer (a1) (a2) and for the CPE Investigators of the Toronto Invasive Bacterial Diseases Network (a7)...

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