Hostname: page-component-8448b6f56d-cfpbc Total loading time: 0 Render date: 2024-04-24T08:25:21.688Z Has data issue: false hasContentIssue false

Impact of the Use of Procalcitonin Assay in Hospitalized Adult Patients with Pneumonia at a Community Acute Care Hospital

Published online by Cambridge University Press:  02 January 2015

Janet L. Kook*
Affiliation:
Hoag Memorial Hospital Presbyterian, Newport Beach, California
Stephanie R. Chao
Affiliation:
Hoag Memorial Hospital Presbyterian, Newport Beach, California
Jennifer Le
Affiliation:
University of California at San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences, La Jolla, California
Philip A. Robinson
Affiliation:
Hoag Memorial Hospital Presbyterian, Newport Beach, California
*
Hoag Memorial Hospital Presbyterian, Pharmacy Department, One Hoag Drive, Newport Beach, CA 92658-6100 (janet.kook@hoag.org)

Abstract

A retrospective, quasi-experimental cohort study compared antibiotic use before and after implementation of a procalcitonin assay at a community acute care hospital. This study demonstrated that the implementation of the procalcitonin assay was associated with a decrease in antibiotic days of therapy in adult patients with pneumonia.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Shiley, KT, Lautenbach, E, Lee, I. The use of antimicrobial agents after diagnosis of viral respiratory tract infections in hospitalized adults: antibiotics or anxiolytics? Infect Control Hosp Epidemiol 2010;31:11771183.Google Scholar
2. Harbarth, S, Holeckova, K, Froidevaux, C, et al. Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 2001;164:396402.Google Scholar
3. Müller, B, Becker, KL, Schadinger, H, et al. Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 2000;28:977983.Google Scholar
4. Meisner, M. Procalcitonin: experience with a new diagnostic tool for bacterial infection and systemic inflammation. J Lab Med 1999;23:263272.Google Scholar
5. Schuetz, P, Christ-Crain, M, Wolbers, M, et al. Effect of procal-citonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP Randomized Controlled Trial. JAMA 2009;302:10591066.Google Scholar
6. Christ-Crain, M, Jaccard-Stolz, D, Bingisser, R, et al. Effect of pro-calcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 2004;363:600607.CrossRefGoogle ScholarPubMed
7. Procalcitonin reference ranges/interpretation of results. Thermo Scientific. Available at: http://www.procalcitonin.com/default.aspx?tree =_3_4&key = product_lrti_reference_values. Accessed February 10, 2010.Google Scholar