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Hospital-Onset Clostridium difficile Infection Rates in Persons with Cancer or Hematopoietic Stem Cell Transplant: A C3IC Network Report

  • Mini Kamboj (a1), Crystal Son (a1), Sherry Cantu (a2), Roy F. Chemaly (a2), Jeanne Dickman (a3), Erik Dubberke (a4) (a5), Lisa Engles (a6), Theresa Lafferty (a7), Gale Liddell (a8), Mary Ellen Lesperance (a6), Julie E. Mangino (a3), Stacy Martin (a9), Jennie Mayfield (a4), Sapna A. Mehta (a10), Susan O'Rourke (a11), Cheryl S. Perego (a2), Randy Taplitz (a12), Janet Eagan (a1) and Kent A. Sepkowitz (a1)...


A multicenter survey of 11 cancer centers was performed to determine the rate of hospital-onset Clostridium difficile infection (HO-CDI) and surveillance practices. Pooled rates of HO-CDI in patients with cancer were twice the rates reported for all US patients (15.8 vs 7.4 per 10,000 patient-days). Rates were elevated regardless of diagnostic test used.


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