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Healthcare Worker with “Pertussis”: Consequences of a False-Positive Polymerase Chain Reaction Test Result

  • David J. Weber (a1) (a2) (a3), Melissa B. Miller (a1) (a2) (a3), Rebecca H. Brooks (a1) (a2) (a3), Vickie M. Brown (a1) (a2) (a3) and William A. Rutala (a1) (a2) (a3)...


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Corresponding author

Bioinformatics, CB 7030, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7030 (


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1.von Konig, CHW, Halperin, S, Riffelmann, M, Guiso, N. Pertussis of adults and children. Lancet Infect Dis 2002;2:744750.
2.Cherry, JD. The epidemiology of pertussis: a comparison of the epidemiology of the disease pertussis with the epidemiology of Bordetella pertussis infection. Pediatrics 2005;115:14221427.
3.Preventing tetanus, diphtheria, and pertussis among adults: use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP) and recommendation of ACIP, supported by the Healthcare Infection Control Practices Advisory Committee (HICPAC), for use of Tdap among health-care personnel. MMWR Recomm Rep 2006;55(RR-17):137.
4.Centers for Disease Control and Prevention (CDC). Guidelines for the control of pertussis outbreaks (amendments made in 2005 and 2006). Atlanta, GA: CDC, 2000. Accessed April 1, 2009.
5.American Academy of Pediatrics. Pertussis. In: Pickering, LK, Baker, CJ, Long, SS, McMillan, JA, eds. Red Book: 2006 Report of the Committee on Infectious Diseases. 27th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2006:498520.
6.Knorr, L, Fox, JD, Tilley, PAG, Ahmed-Bentley, J. Evaluation of real-time PCR for diagnosis of Bordetella pertussis infection. BMC Infect Dis 2006;6:62.
7.Centers for Disease Control and Prevention (CDC). Hospital-acquired pertussis among newborns—Texas, 2004. MMWR Morb Mortal Wkly Rep 2008;57:600603.
8.Bryant, KA, Humbaugh, K, Brothers, K, et al.Measures to control an outbreak of pertussis in a neonatal intermediate care nursery after exposure to a healthcare worker. Infect Control Hosp Epidemiol 2006;27:541545.
9.Yih, WK, Silva, EA, Ida, J, Harrington, N, Lett, SM, George, H. Bordetella holmesii-like organisms isolated from Massachusetts patients with pertussis-like symptoms. Emerg Infect Dis 1999;5:441443.
10.Russell, FM, Davis, JM, Whipp, MJ, et al.Severe Bordetella holmesii infection in a previously healthy adolescent confirmed by gene sequence analysis. Clin Infect Dis 2001;33:129130.
11.Dorbecker, C, Licht, C, Korber, F, et al.Community-acquired pneumonia due to Bordetella holmesii in a patient with frequently relapsing nephrotic syndrome. J Infect 2007;54:e203e205.
12.Centers for Disease Control and Prevention (CDC). Outbreaks of respiratory illness mistakenly attributed to pertussis—New Hampshire, Massachusetts, and Tennessee, 2004–2006. MMWR Morb Mortal Wkly Rep 2007;56:837842.


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