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Guideline-Concordant Versus Discordant Antimicrobial Therapy in Patients With Community-Onset Complicated Intra-abdominal Infections

  • Lori L. Huang (a1) (a2), Trevor C. Van Schooneveld (a3) (a4), Robert D. Huang (a3) (a5), Keith M. Olsen (a2), Mark E. Rupp (a3) (a4) and Alan E. Gross (a2) (a3) (a6) (a7)...


Overall IDSA/SIS intra-abdominal infection guideline compliance was not associated with improved outcomes; however, there was a longer time to active therapy (P=.024) and higher mortality (P=.077) if empiric therapy was too narrow per guidelines. These findings support the need for the implementation of customized institutional guidelines adapted from the IDSA/SIS guidelines.

Infect Control Hosp Epidemiol 2016;37:855–858


Corresponding author

Address correspondence to Alan E. Gross, 833 South Wood Street, 164 PHARM, Chicago, IL 60612 (


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PREVIOUS PRESENTATION. This study was presented in part as a poster (#1939) at the Interscience Conference on Antimicrobial Agents and Chemotherapy in Denver, Colorado, on September 13, 2013.



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