Skip to main content Accessibility help

Evaluation of a Pulsed-Xenon Ultraviolet Room Disinfection Device for Impact on Hospital Operations and Microbial Reduction

  • Mark Stibich (a1), Julie Stachowiak (a1), Benjamin Tanner (a2), Matthew Berkheiser (a3), Linette Moore (a3), Issam Raad (a4) and Roy F. Chemaly (a4)...


This study evaluated the use of pulsed-xenon ultraviolet (PX-UV) room disinfection by sampling frequently touched surfaces in vancomycin-resistant enterococci (VRE) isolation rooms. The PX-UV system showed a statistically significant reduction in microbial load and eliminated VRE on sampled surfaces when using a 12-minute multiposition treatment cycle.


Corresponding author

1250 South Capital of Texas Highway, Austin, TX 78746 (


Hide All
1.Carling, PC, Von Beheren, S, Kim, P, Woods, C. Intensive care unit environmental cleaning: an evaluation in sixteen hospitals using a novel assessment tool. J Hosp Infec 2008;68(1):3944.
2.Huang, SS, Datta, R, Platt, R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med 2006;166(18):19451951.
3.Drees, M, Snydman, DR, Schmid, CH, et al.Prior environmental contamination increases the risk of acquisition of vancomycin-resistant enterococci. Clin Infect Dis 2008;46(5):678685.
4.Eckstein, BC, Adams, DA, Eckstein, EC, Sethi, AK, Yadavalli, G, Donskey, GJ. Reduction of Clostridium difficile and vancomycin-resistant Enterococcus contamination of environmental surfaces after an intervention to improve cleaning methods. BMC Infect Dis 2007;7:61.
5.Mayfield, JL, Leet, T, Miller, J, Mundy, LM. Environmental control to reduce transmission of Clostridium difficile. Clin Infect Dis 2000;31(4):9951000.
6.Wener, K, Willey, S, Eyre-Kelly, J, Duncan, R. Reduction in nosocomial Clostridium difficile infection (CDI) rates after terminal hypochlorite room cleaning. In: Program and abstracts of the Fifth Decennial International Conference on Healthcare-Associated Infection; March 18-22, 2010; Atlanta, GA. Abstract 200.
7.Kowalski, W. UVGI deactivation theory. In: Ultraviolet Germicidal Irradiation Handbook. New York: Springer; 2009:1750.
8.Kowalski, W. Pulsed UV systems. In: Ultraviolet Germicidal Irradiation Handbook. New York: Springer; 2009:383398.
9.Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Disk Susceptibility Tests: Approved Standards—10th Edition. Wayne, PA: CLSI; 2009. CLSI document M02-A10.


Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed