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Eikenella corrodens

  • Charles W. Stratton (a1) and Michael D. Decker (a1)


It is thought that the first person to describe the organism subsequently known as Eikenella corrodens was Sverre Henriksen, who in 1948 reported the isolation of three gram-negative anaerobic rods with concentrically spreading colonies and a tendency to pit the agar. This corroding of the agar was seen most reliably with strain AJ, a nonmotile organism isolated from a perineal abscess. Two years later, Per Holm found that a gram-negative anaerobic organism resembling the influenza bacillus was often isolated from specimens of pus, examined for the presence of actinomycetes. Because of its appearance on blood agar, Holm proposed calling this organism the “corroding bacillus.” In 1958, Eiken studied 1,097 anaerobes isolated from 798 patients; of these, 61 corresponded in colony and microscopic morphology with the corroding bacillus.


Corresponding author

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232


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1.Henriksen, SV: Studies in Gram-negative anaerobes. II. Gram-negative anaerobic rods with spreading colonies. Acta Pathol Microbiol Immunol Scand 1948; 25:368375.
2.Holm, P: Studies on the aetiology of human actinomycosis. I. The other microbes of actinomycosis and their importance. Acta Path of Microbiol Immunol Scand 1950; 27:73767404.
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10.Jackson, FL, Goodman, YE, Bel, FR, et al: Taxonomic status of facultative and strictly anaerobic “corroding bacilli” that have been classified as Bacteroides corrodens. J Med Microbiol 1971; 4:171184.
11.Jackson, FL, Goodman, YE: Transfer of the facultatively anaerobic organism Bacteroides corrodens Eiken to a new genus, Eikenella. International Journal of Systematic Bacteriology 1972; 22:7377.
12.Riley, PS, Tatum, HW, Weaver, RE: Identity of HB-1 of King and Eikenella corrodens (Eiken) Jackson and Goodman. International Journal of Systematic Bacteriology 1973; 23:7576.
13.Brooks, GF, O'Donoghue, JM, Rissing, JP, et al: Eikenella corrodens, a recently recognized pathogen: Infections in medical-surgical patients and in association with methylphenidate abuse. Medicine 1974; 53:325342.
14.Goldstein, EJC, Agyare, EO, Silletti, R: Comparative growth of Eikenella corrodens on 15 media in three atmospheres of incubation. J Clin Microbiol 1981; 13:951953.
15.Suwanagool, S, Rothkopf, MM, Smith, SM, et al: Pathogenicity of Eikenella corrodens in humans. Arch Intern Med 1983; 143:22652269.
16.Brill, CB, Pearlstein, LS, Kaplan, JM, et al: CNS infections caused by Eikenella corrodens. Arch Neurol 1982; 39:431432.
17.Goldstein, EJC, Cherubin, CE, Shulman, M: Comparison of microtiter broth dilution and agar dilution methods for susceptibility testing of Eikenella corrodens. Antimicrob Agents Chemother 1983; 23:4245.
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19.Maliszewski, CR, Badger, SJ: Group and type antigens of Eikenella corrodens. Abstracts of the Annual Meeting of the American Society for Microbiology, 1980, p 94.
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21.Goldstein, EJC, Gombert, ME, Agyare, EO: Susceptibility of Eikenella corrodens to newer beta-lactam antibiotics. Antimicrob Agents Chemother 1980; 18:832833.
22.Goldstein, EJC, Sutter, VL, Finegold, SM: Susceptibility of Eikenella corrodens to ten cephalosporins. Antimicrob Agents Chemother 1978; 14:639641.


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