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Ecological Study of the Effectiveness of Isolation Precautions in the Management of Hospitalized Patients Colonized or Infected With Acinetobacter baumannii

Published online by Cambridge University Press:  02 January 2015

Houssein Gbaguidi-Haore ,
Sophie Legast ,
Michelle Thouverez ,
Xavier Bertrand  and
Daniel Talon
Houssein Gbaguidi-Haore
Affiliation:
Service d'Hygiène Hospitalière et d'Epidémiologie Moléculaire, Centre Hospitalier Universitaire Jean Minjoz, Besançon, France
Sophie Legast
Affiliation:
Service d'Hygiène Hospitalière et d'Epidémiologie Moléculaire, Centre Hospitalier Universitaire Jean Minjoz, Besançon, France
Michelle Thouverez
Affiliation:
Service d'Hygiène Hospitalière et d'Epidémiologie Moléculaire, Centre Hospitalier Universitaire Jean Minjoz, Besançon, France
Xavier Bertrand*
Affiliation:
Service d'Hygiène Hospitalière et d'Epidémiologie Moléculaire, Centre Hospitalier Universitaire Jean Minjoz, Besançon, France
Daniel Talon
Affiliation:
Service d'Hygiène Hospitalière et d'Epidémiologie Moléculaire, Centre Hospitalier Universitaire Jean Minjoz, Besançon, France
*
Service d'Hygiène Hospitalière, Centre Hospitalier Universitaire Jean Minjoz, Besançon, 25030 Besançon cedex, France (xavier.bertrand@univ-fcomte.fr)
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Abstract

Objective.

To assess the impact of isolation precautions on the incidence of patients colonized or infected with Acinetobacter baumannii (case patients) in a university hospital during the period from 1999 to 2006.

Design.

Ecological study.

Setting.

The Besançon University Hospital in France, a 1,200-bed acute care hospital with approximately 50,000 admissions per year.

Methods.

Using Poisson regression analysis, we evaluated a total of 350,000 patient-days to determine the annual incidence of case patients. This annual incidence was used as the outcome variable, and infection control practices, antibiotic use, and other aggregated data regarding patients' age, sex, McCabe score, and immune status were used as covariates.

Results.

The implementation of isolation precautions was independently and negatively associated with the incidence of patients colonized or infected with A. baumannii (relative risk, 0.50 [95% confidence interval, 0.40–0.64]; P < .001).

Conclusions.

Our study suggests that the implementation of isolation precautions, in addition to standard precautions, effectively prevents the spread of A. baumannii in a hospital setting.

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 29 , Issue 12 , December 2008 , pp. 1118 - 1123
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

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