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Caution, not causality: The limitations of risk factor and outcome research on ventilator-associated events

Published online by Cambridge University Press:  03 May 2021

Kelly A. Cawcutt*
Affiliation:
Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska
Trevor C. Van Schooneveld
Affiliation:
Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska
*
Author for correspondence: Kelly Cawcutt, E-mail: kelly.cawcutt@unmc.edu

Abstract

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Type
Commentary
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

Klompas, M, Branson, R, Eichenwald, EC, et al. Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol 2014;35:S133S154.CrossRefGoogle ScholarPubMed
Klompas, M. Barriers to the adoption of ventilator-associated events surveillance and prevention. Clin Microbiol Infect 2019;25:11801185.CrossRefGoogle ScholarPubMed
Fan, Y, Gao, F, Wu, Y, Zhang, J, Zhu, M, Xiong, L. Does ventilator-associated event surveillance detect ventilator-associated pneumonia in intensive care units? A systematic review and meta-analysis. Crit Care 2016;20:113.CrossRefGoogle ScholarPubMed
Harris, BD, Thomas, GA, Greene, MH, Spires, SS, Talbot, TR. Ventilator bundle compliance and risk of ventilator-associated events. Infect Control Hosp Epidemiol 2018;39:637643.CrossRefGoogle ScholarPubMed
Zhu, S, Wang, W, Kang, Y, et al. Clinical outcomes and risk factors for mortality from ventilator-associated events: a registry-based cohort study among 30,830 intensive care unit patients. Infect Control Hosp Epidemiol 2021. doi: 10.1017/ice.2021.64.CrossRefGoogle ScholarPubMed
Posa, P, Barnes, D, Bogan, B, et al. 776: Compliance with spontaneous breathing trial protocol associated with lower VAE rates. Crit Care Med 2014;42:A1547.CrossRefGoogle Scholar
Klompas, M. Potential strategies to prevent ventilator-associated events. Am J Resp Crit Care Med 2015;192:14201430.CrossRefGoogle ScholarPubMed
Klompas, M, Anderson, D, Trick, W, et al. The preventability of ventilator-associated events. The CDC prevention epicenters wake up and breathe collaborative. Am Respir Crit Care Med 2015;191:292301.CrossRefGoogle ScholarPubMed
Rohde, JM, Dimcheff, DE, Blumberg, N, et al. Healthcare-associated infection after red blood-cell transfusion: a systematic review and meta-analysis. JAMA 2014;311:13171326.CrossRefGoogle ScholarPubMed