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Antibiotic Susceptibility of Urinary Isolates in Nursing Home Residents Consuming Cranberry Capsules Versus Placebo

  • Gregory R. Madden (a1), Stephanie M. Argraves (a2), Peter H. Van Ness (a2) (a3) and Manisha Juthani-Mehta (a4)


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Corresponding author

Address correspondence to Gregory Madden, MD, Yale University School of Medicine, Department of Internal Medicine Residency Programs, PO Box 208033, New Haven, CT 06520-8033 (


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2.Avorn, J, Monane, M, Gurwitz, H, Glynn, R, Choodnovskiy, I, Lipsitz, L. Reduction of bacteriuria and pyuria after ingestion of cranberry juice. JAMA 1994;271:751754.
3.Jepson, RG, Williams, G, Craig, JC. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev 2012;10:CD001321.
4.Ofek, I, Goldhar, J, Zafriri, D, Lis, H, Adar, R, Sharon, N. Anti-Escherichia-coli adhesin activity of cranberry and blueberry juices. N Engl J Med 1991;324:15991599.
5.Bianco, L, Perrelli, E, Towle, V, Van Ness, PH, Juthani-Mehta, M. Pilot randomized controlled dosing study of cranberry capsules for reduction of bacteriuria plus pyuria in female nursing home residents. J Am Geriatr Soc 2012;60:11801181.
6.Das, R, Perrelli, E, Towle, V, Van Ness, PH, Juthani-Mehta, M. Antimicrobial susceptibility of bacteria isolated from urine samples obtained from nursing home residents. Infect Control Hosp Epidemiol 2009;30:11161119.
7.Jagielski, M, Sztabińska-Koncka, H, Rastawicki, W, Szych, J, Kałuzewski, S, Mrozowska, A. Occurrence of P.fimbrii in strains from selected genera of Enterobacteriaceae. Med Dosw Mikrobiol 1992;44:97107.
8.Ahuja, S, Kaack, B, Roberts, J. Loss of fimbrial adhesion with the addition of Vaccinum macrocarpon to the growth medium of P-fimbriated Escherichia coli. J Urol 1998;159:559562.
9.Harjai, K, Gupta, RK, Sehgal, H. Attenuation of quorum sensing controlled virulence of Pseudomonas aeruginosa by cranberry. Indian J Med Res 2014;139:446453.


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