Skip to main content Accessibility help
×
Home
Hostname: page-component-559fc8cf4f-s65px Total loading time: 0.347 Render date: 2021-03-07T18:45:33.991Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": false, "newCiteModal": false, "newCitedByModal": true }

Implementation of infectious diseases rapid molecular diagnostic tests and antimicrobial stewardship program involvement in acute-care hospitals

Published online by Cambridge University Press:  16 October 2020

Maiko Kondo
Affiliation:
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York
Matthew S. Simon
Affiliation:
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York
Lars F. Westblade
Affiliation:
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York
Stephen G. Jenkins
Affiliation:
Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York
N. Esther Babady
Affiliation:
Clinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York
Angela S. Loo
Affiliation:
Department of Pharmacy, NewYork-Presbyterian Hospital, New York, New York
David P. Calfee
Affiliation:
Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York
Corresponding

Abstract

A survey of acute-care hospitals found that rapid molecular diagnostic tests (RMDTs) have been widely adopted. Although many hospitals use their antimicrobial stewardship team and/or guidelines to help clinicians interpret results and optimize treatment, opportunities to more fully achieve the potential benefits of RMDTs remain.

Type
Concise Communication
Copyright
© The Author(s), 2020. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below.

Footnotes

ADDITIONAL PRESENTATION. An abstract summarizing the results of this study was accepted for presentation at the 6th Decennial International Conference on Healthcare Associated Infections, Atlanta, Georgia, March 26–30, 2020. The conference was canceled, however, due to the COVID-19 crisis. Abstracts will be published in a supplementary issue of Infection Control and Hospital Epidemiology.

References

Timbrook, TT, Morton, JB, McConeghy, KW, Caffrey, AR, Mylonakis, E, LaPlante, KL. The effect of molecular rapid diagnostic testing on clinical outcomes in bloodstream infections: a systematic review and meta-analysis. Clin Infect Dis 2017;64:1523.CrossRefGoogle ScholarPubMed
Beal, SG, Tremblay, EE, Toffel, S, Velez, L, Rand, KH. A gastrointestinal PCR panel improves clinical management and lowers health care costs. J Clin Microbiol 2017;56(1):e01457-17.CrossRefGoogle ScholarPubMed
Mulpuru, S, Aaron, SD, Ronksley, PE, Lawrence, N, Forster, AJ. Hospital resource utilization and patient outcomes associated with respiratory viral testing in hospitalized patients. Emerg Infect Dis 2015;21:13661371.CrossRefGoogle ScholarPubMed
Evans, M, Merkel, KG, Harder, J, Rose, DT. Impact of the implementation of a rapid meningitis/encephalitis multiplex polymerase chain reaction panel on IV acyclovir duration: multicenter, retrospective cohort of adult and pediatric patients. Diagn Microbiol Infect Dis 2020;96(2):114935.CrossRefGoogle ScholarPubMed
Society for Healthcare Epidemiology of America Research Network website. https://www.shea-online.org/index.php/practice-resources/research/shea-research-network Accessed August 28, 2020.Google Scholar
American Society for Microbiology. Subscriptions. Clinmicronet. Available at: https://www.asm.org/Forms/Subscriptions. Accessed August 28, 2020.Google Scholar
Messacar, K, Parker, SK, Todd, JK, Dominguez, SR. Implementation of rapid molecular infectious disease diagnostics: the role of diagnostic and antimicrobial stewardship. J Clin Microbiol 2017;55:715723.CrossRefGoogle ScholarPubMed
Graf, EH, Pancholi, P. Appropriate use and future directions of molecular diagnostic testing. Curr Infect Dis Rep 2020;22:5.CrossRefGoogle ScholarPubMed
Patel, R, Fang, FC. Diagnostic stewardship: opportunity for a laboratory-infectious diseases partnership. Clin Infect Dis 2018;67:799801.CrossRefGoogle ScholarPubMed
Donner, LM, Campbell, WS, Lyden, E, Van Schooneveld, TC. Assessment of rapid blood-culture identification result interpretation and antibiotic prescribing practices. J Clin Microbiol 2017;55:14961507.CrossRefGoogle ScholarPubMed

Kondo et al. supplementary material

Table S1

File 41 KB

Altmetric attention score

Full text views

Full text views reflects PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.

Total number of HTML views: 18
Total number of PDF views: 34 *
View data table for this chart

* Views captured on Cambridge Core between 16th October 2020 - 7th March 2021. This data will be updated every 24 hours.

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Implementation of infectious diseases rapid molecular diagnostic tests and antimicrobial stewardship program involvement in acute-care hospitals
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Implementation of infectious diseases rapid molecular diagnostic tests and antimicrobial stewardship program involvement in acute-care hospitals
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Implementation of infectious diseases rapid molecular diagnostic tests and antimicrobial stewardship program involvement in acute-care hospitals
Available formats
×
×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *