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Ertapenem Prophylaxis Associated With an Increased Risk of Clostridium difficile Infection Among Surgical Patients

Published online by Cambridge University Press:  17 August 2015

Seungwon Lee
Affiliation:
Department of Hospital Epidemiology and Infection Control, University of California San Francisco Medical Center, San Francisco, California
Priya Prasad
Affiliation:
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California
Matthew Lin
Affiliation:
Department of Surgery, University of California San Francisco, San Francisco, California
Susan Garritson
Affiliation:
Department of Hospital Epidemiology and Infection Control, University of California San Francisco Medical Center, San Francisco, California
Amy Nichols
Affiliation:
Department of Hospital Epidemiology and Infection Control, University of California San Francisco Medical Center, San Francisco, California
Catherine Liu
Affiliation:
Division of Infectious Diseases, Department of Medicine, University of California San Francisco, San Francisco, California.
Corresponding
E-mail address:

Abstract

A case-control study was conducted to determine risk factors for hospital-onset Clostridium difficile infection among patients admitted to 2 surgical units. Ertapenem prophylaxis was significantly associated with C. difficile infection risk (odds ratio, 3.13 [95% CI, 1.13–8.68], P=.028) and may offer an antimicrobial stewardship target among surgical patients.

Infect. Control Hosp. Epidemiol. 2015;36(11):1351–1354

Type
Concise Communications
Copyright
© 2015 by The Society for Healthcare Epidemiology of America. All rights reserved 

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Footnotes

Presented in part: IDWeek 2014; Philadelphia, PA; October 8-12, 2014 (Abstract 1623).

References

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